FOG13932
EOG8GTHTW

sce:LHS1

Genes: 34

SGD Description
Molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway


PomBase Description
ER heat shock protein Lsh1 (predicted)


AspGD Description
ER nucleotide exchange factor; expression enhanced by maltose; expression induced by tunicamycin and DTT


References

Craven RA, et al. (1996 Jun 3). A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors.

Travers KJ, et al. (2000 Apr 28). Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation.

Steel GJ, et al. (2004 Jan 2). Coordinated activation of Hsp70 chaperones.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%