FOG13931
EOG8GTHVB

sce:absent

Genes: 7

PomBase Description
transmembrane transporter (predicted)


AspGD Description
Ortholog(s) have purine nucleobase transmembrane transporter activity, role in hypoxanthine transport and Golgi apparatus, fungal-type vacuole, plasma membrane localization


References

Bignami M, et al. (1982 Aug). Evaluation of 2 different genetic markers for the detection of frameshift and missense mutagens in A. nidulans.

Suárez T, et al. (1991 Dec). The uaY positive control gene of Aspergillus nidulans: fine structure, isolation of constitutive mutants and reversion patterns.

Diallinas G, et al. (1994). Genetic and molecular characterisation of purine permease genes of Aspergillus nidulans reveals a novel family of transporters conserved in prokaryotes and eukaryotes.

Scazzocchio C, et al. (1994). The purine degradation pathway, genetics, biochemistry and regulation.

Diallinas G, et al. (1995 Apr 14). Genetic and molecular characterization of a gene encoding a wide specificity purine permease of Aspergillus nidulans reveals a novel family of transporters conserved in prokaryotes and eukaryotes.

Valdez-Taubas J, et al. (2000 Jul). Protein expression and subcellular localization of the general purine transporter UapC from Aspergillus nidulans.

Amillis S, et al. (2004 Apr). Transcription of purine transporter genes is activated during the isotropic growth phase of Aspergillus nidulans conidia.

Cecchetto G, et al. (2004 Jan 30). The AzgA purine transporter of Aspergillus nidulans. Characterization of a protein belonging to a new phylogenetic cluster.

Goudela S, et al. (2006 Jul-Aug). Comparative kinetic analysis of AzgA and Fcy21p, prototypes of the two major fungal hypoxanthine-adenine-guanine transporter families.

Pantazopoulou A, et al. (2007 Jul). Differential physiological and developmental expression of the UapA and AzgA purine transporters in Aspergillus nidulans.

Pantazopoulou A, et al. (2007 Nov). Fungal nucleobase transporters.

Vlanti A, et al. (2008 May). The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis.

Papageorgiou I, et al. (2008 Oct 24). Specific interdomain synergy in the UapA transporter determines its unique specificity for uric acid among NAT carriers.

Mansfield TA, et al. (2009 Jan 22). AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.

Bitsikas V, et al. (2011 Jan). Hypertonic conditions trigger transient plasmolysis, growth arrest and blockage of transporter endocytosis in Aspergillus nidulans and Saccharomyces cerevisiae.

Karachaliou M, et al. (2013 Apr). The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals.

Krypotou E, et al. (2014 Jul). Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%