FOG13701
EOG8HDR9P

sce:SNF12;RSC6

Genes: 33

SGD Description
73 kDa subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; relocates to the cytosol under hypoxic conditions; deletion mutants are temperature-sensitive; SNF12 has a paralog, RSC6, that arose from the whole genome duplication|Component of the RSC chromatin remodeling complex; essential for mitotic growth; RSC6 has a paralog, SNF12, that arose from the whole genome duplication


PomBase Description
SWI/SNF and RSC complex subunit Ssr3


AspGD Description
Ortholog(s) have RSC complex, SWI/SNF complex, cytosol localization


References

Cairns BR, et al. (1996 Dec 27). RSC, an essential, abundant chromatin-remodeling complex.

Cairns BR, et al. (1996 Sep 1). Essential role of Swp73p in the function of yeast Swi/Snf complex.

Treich I, et al. (1998 Aug 15). Direct interaction between Rsc6 and Rsc8/Swh3,two proteins that are conserved in SWI/SNF-related complexes.

Lorch Y, et al. (1999 Feb 5). Histone octamer transfer by a chromatin-remodeling complex.

Moreira JM, et al. (1999 May 17). Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Cairns BR, et al. (1999 Nov). Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

Saha A, et al. (2002 Aug 15). Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Chai B, et al. (2002 Jun). Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway.

Smith CL, et al. (2003 Feb). Structural analysis of the yeast SWI/SNF chromatin remodeling complex.

Hsu JM, et al. (2003 May). The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

Wilson B, et al. (2006 Feb). The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.

Monahan BJ, et al. (2008 Aug). Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Zilio N, et al. (2014 Sep 15). A novel histone deacetylase complex in the control of transcription and genome stability.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%