FOG13516
EOG8HT7D5

sce:CUS2

Genes: 27

SGD Description
Putative checkpoint factor in transcription; binds to U2 snRNA and Prp11p; may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)


PomBase Description
U2 snRNP-associated protein Uap2


AspGD Description
Ortholog(s) have U2 snRNP, U2-type spliceosomal complex localization


References

McKinney R, et al. (1997 Nov). Molecular characterization of a novel fission yeast gene spUAP2 that interacts with the splicing factor spU2AF59.

Yan D, et al. (1998 Sep). CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif.

Beales M, et al. (2000 Aug). Mutations in the large subunit of U2AF disrupt pre-mRNA splicing, cell cycle progression and nuclear structure.

Perriman R, et al. (2000 Jan 1). ATP can be dispensable for prespliceosome formation in yeast.

Ochotorena IL, et al. (2001 Aug). Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturation.

Stevens SW, et al. (2002 Jan). Composition and functional characterization of the yeast spliceosomal penta-snRNP.

Xu YZ, et al. (2007 Dec 14). Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assembly.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%