FOG13506
EOG8HX3G7

sce:STT3

Genes: 33

SGD Description
Subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis


PomBase Description
oligosaccharyltransferase subunit Stt3


AspGD Description
Oligosaccharyltransferase complex subunit; putative transmembrane protein localised in the ER; expression enhanced by maltose


References

Yoshida S, et al. (1995 Oct 16). STT3, a novel essential gene related to the PKC1/STT1 protein kinase pathway, is involved in protein glycosylation in yeast.

Zufferey R, et al. (1995 Oct 16). STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo.

Karaoglu D, et al. (1997 Dec 19). The highly conserved Stt3 protein is a subunit of the yeast oligosaccharyltransferase and forms a subcomplex with Ost3p and Ost4p.

Spirig U, et al. (1997 Nov). The STT3 protein is a component of the yeast oligosaccharyltransferase complex.

Yoshida S, et al. (1999 Apr). Schizosaccharomyces pombe stt3+ is a functional homologue of Saccharomyces cerevisiae STT3 which regulates oligosaccharyltransferase activity.

Kim H, et al. (2000 Feb 15). Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase.

Yan Q, et al. (2002 Dec 6). Studies on the function of oligosaccharyl transferase subunits. Stt3p is directly involved in the glycosylation process.

Decottignies A, et al. (2003 Mar). Schizosaccharomyces pombe essential genes: a pilot study.

Spirig U, et al. (2005 Dec). The 3.4-kDa Ost4 protein is required for the assembly of two distinct oligosaccharyltransferase complexes in yeast.

Yan A, et al. (2005 Dec). Two oligosaccharyl transferase complexes exist in yeast and associate with two different translocons.

Schwarz M, et al. (2005 Dec 5). Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

Chavan M, et al. (2005 Jun 17). Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Yan A, et al. (2005 May 17). Studies of yeast oligosaccharyl transferase subunits using the split-ubiquitin system: topological features and in vivo interactions.

Kim H, et al. (2005 May 27). Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Huang C, et al. (2012 Sep 21). Eukaryotic N-glycosylation occurs via the membrane-anchored C-terminal domain of the Stt3p subunit of oligosaccharyltransferase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%