FOG13383
EOG8J3V3Q

sce:TOA2

Genes: 32

SGD Description
TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa1p, for ribosomal protein gene transcription in vivo; homologous to smallest subunit of human and Drosophila TFIIA; protein abundance increases in response to DNA replication stress


PomBase Description
transcription factor TFIIA complex small subunit Toa2 (predicted)


AspGD Description
Ortholog(s) have RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly, TBP-class protein binding activity


References

Ranish JA, et al. (1991 Oct 15). The yeast general transcription factor TFIIA is composed of two polypeptide subunits.

Ranish JA, et al. (1992 Feb 28). Isolation of two genes that encode subunits of the yeast transcription factor IIA.

Tan S, et al. (1996 May 9). Crystal structure of a yeast TFIIA/TBP/DNA complex.

Titov AA, et al. (1999 Oct 18). The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus.

Kraemer SM, et al. (2001 Mar). TFIIA interacts with TFIID via association with TATA-binding protein and TAF40.

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Herrero S, et al. (2011 May). The Aspergillus nidulans CENP-E kinesin motor KipA interacts with the fungal homologue of the centromere-associated protein CENP-H at the kinetochore.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Harting R, et al. (2013 Dec). Interplay of the fungal sumoylation network for control of multicellular development.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Montes M, et al. (2017 Feb). RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%