FOG13371
EOG8J6Q66

sce:AFG3;YTA12

Genes: 58

SGD Description
Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging|Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes


PomBase Description
mitochondrial m-AAA protease Yta12 (predicted)


AspGD Description
Ortholog(s) have ATP binding, ATPase activity, metallopeptidase activity, role in protein complex assembly, signal peptide processing and m-AAA complex, mitochondrial inner boundary membrane localization


References

Guelin E, et al. (1994 Oct). Sequence of the AFG3 gene encoding a new member of the FtsH/Yme1/Tma subfamily of the AAA-protein family.

Tzagoloff A, et al. (1994 Oct 21). A new member of a family of ATPases is essential for assembly of mitochondrial respiratory chain and ATP synthetase complexes in Saccharomyces cerevisiae.

Schnall R, et al. (1994 Sep). Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex.

Arlt H, et al. (1996 Jun 14). The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria.

Arlt H, et al. (1998 Aug 17). The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 57 genes with posterior transmembrane prediction > 50%