FOG12702
EOG8KWH82

sce:RLI1

Genes: 21

SGD Description
Essential Fe-S protein; required for ribosome biogenesis, translation initiation/termination; facilitates binding of multifactor complex (MFC) of initiation factors to small ribosomal subunit; Dom34-Hbs1 complex and Rli1p work in dissociating inactive ribosomes, thereby facilitating translation restart; forms complex with Lto1p and Yae1p; dependency on ROS-labile FeS clusters, activity in nuclear ribosomal-subunit export impaired by mild oxidative stress


PomBase Description
iron-sulfur ATPase involved in ribosome biogenesis and translation Rli1 (predicted)


AspGD Description
Ortholog(s) have iron ion binding activity


References

Dong J, et al. (2004 Oct 1). The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly.

Kispal G, et al. (2005 Feb 9). Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria.

Yarunin A, et al. (2005 Feb 9). Functional link between ribosome formation and biogenesis of iron-sulfur proteins.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%