FOG12589
EOG8M63ZB

sce:BPH1

Genes: 32

SGD Description
Protein homologous to Chediak-Higashi syndrome and Beige proteins; both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting


PomBase Description
beige protein homolog Lvs1 (predicted)


AspGD Description
Ortholog(s) have cytosol localization


References

Shiflett SL, et al. (2004 Sep). Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Rains A, et al. (2017). <i>Ypt4</i> and <i>lvs1</i> regulate vacuolar size and function in <i>Schizosaccharomyces pombe</i>.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 24 genes with posterior transmembrane prediction > 50%