FOG12271
EOG8N02W3

sce:TAF6

Genes: 33

SGD Description
Subunit (60 kDa) of TFIID and SAGA complexes; involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4; relocalizes to the cytosol in response to hypoxia


PomBase Description
histone H4-like TAF Taf6, SAGA complex subunit


AspGD Description
Ortholog(s) have SAGA complex, cytosol, transcription factor TFIID complex localization


References

Poon D, et al. (1995 Aug 29). Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

Grant PA, et al. (1998 Jul 10). A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Birck C, et al. (1998 Jul 24). Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.

Grant PA, et al. (1999 Feb 26). Expanded lysine acetylation specificity of Gcn5 in native complexes.

Sanders SL, et al. (2000 May 5). Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Gangloff YG, et al. (2001 Apr). The histone fold is a key structural motif of transcription factor TFIID.

Selleck W, et al. (2001 Aug). A histone fold TAF octamer within the yeast TFIID transcriptional coactivator.

Gangloff YG, et al. (2001 Mar). Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7.

Sanders SL, et al. (2002 Aug). Molecular characterization of Saccharomyces cerevisiae TFIID.

Martinez E, et al. (2002 Dec). Multi-protein complexes in eukaryotic gene transcription.

Pray-Grant MG, et al. (2002 Dec). The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Sanders SL, et al. (2002 Jul). Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

Leurent C, et al. (2002 Jul 1). Mapping histone fold TAFs within yeast TFIID.

Mitsuzawa H, et al. (2002 May 1). Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF.

Sterner DE, et al. (2002 Sep 3). SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription.

Wu PY, et al. (2004 Jul 23). Molecular architecture of the S. cerevisiae SAGA complex.

Pray-Grant MG, et al. (2005 Jan 27). Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.

Helmlinger D, et al. (2008 Nov 15). The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.

Helmlinger D, et al. (2011 Jun 3). Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex.

Georgakopoulos P, et al. (2013). The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex in Aspergillus nidulans.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 11 genes with posterior transmembrane prediction > 50%