FOG12270
EOG876HH8
EOG8N02W5

sce:MLH2

Genes: 17

SGD Description
Protein involved in mismatch repair and meiotic recombination; only certain frameshift intermediates are mismatch repair substrates; forms a complex with Mlh1p


AspGD Description
Has domain(s) with predicted ATP binding, mismatched DNA binding activity, role in mismatch repair and MutLalpha complex localization


References

Wang TF, et al. (1999 Nov 23). Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.

Harfe BD, et al. (2000 Feb 10). Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.

Abdullah MF, et al. (2004). A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%