FOG12270
EOG876HH8
EOG8N02W5
sce:MLH2
Genes: 17
SGD DescriptionProtein involved in mismatch repair and meiotic recombination; only certain frameshift intermediates are mismatch repair substrates; forms a complex with Mlh1p
AspGD DescriptionHas domain(s) with predicted ATP binding, mismatched DNA binding activity, role in mismatch repair and MutLalpha complex localization
References
Wang TF, et al. (1999 Nov 23). Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.
Harfe BD, et al. (2000 Feb 10). Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.
Abdullah MF, et al. (2004). A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast.