FOG12116
EOG8NCJTT

sce:MDS3;PMD1

Genes: 23

SGD Description
Putative component of the TOR regulatory pathway; negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions; has an N-terminal kelch-like domain; MDS3 has a paralog, PMD1, that arose from the whole genome duplication|Protein with an N-terminal kelch-like domain; putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions; PMD1 has a paralog, MDS3, that arose from the whole genome duplication


References

Benni ML, et al. (1997 Nov). Identification of a new class of negative regulators affecting sporulation-specific gene expression in yeast.

Davis DA, et al. (2002 Dec). Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

McDonald CM, et al. (2009 Feb). The Ras/cAMP pathway and the CDK-like kinase Ime2 regulate the MAPK Smk1 and spore morphogenesis in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%