FOG11682
EOG8PG4FV

sce:PTA1

Genes: 32

SGD Description
Subunit of holo-CPF; holo-CPF is a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII


PomBase Description
mRNA cleavage and polyadenylation specificity factor complex subunit Pta1


AspGD Description
Ortholog(s) have mRNA cleavage and polyadenylation specificity factor complex localization


References

O'Connor JP, et al. (1992 Sep). PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing.

Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Roguev A, et al. (2004 Feb). A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Vanoosthuyse V, et al. (2014 Jun). CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.

Hu W, et al. (2015 Nov 27). Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast.

Wittmann S, et al. (2017 Apr 3). The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 13 genes with posterior transmembrane prediction > 50%