FOG11681
EOG8PG4G1

sce:EXO84

Genes: 29

SGD Description
Exocyst subunit with dual roles in exocytosis and spliceosome assembly; subunit of the the exocyst complex which mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane (PM) prior to SNARE-mediated fusion; required for exocyst assembly and targeting the complex to specific sites on the bud tip PM; associates the U1 snRNP; role in pre-mRNA splicing and prespliceosome formation; possible Cdc28 substrate


PomBase Description
exocyst complex subunit Exo84 (predicted)


AspGD Description
Ortholog(s) have role in Golgi to plasma membrane transport, exocyst assembly, exocyst localization, spliceosomal complex assembly


References

Guo W, et al. (1999 Aug 13). Exo84p is an exocyst protein essential for secretion.

Awasthi S, et al. (2001 Aug 17). New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Boyd C, et al. (2004 Dec 6). Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p.

Dong G, et al. (2005 Dec). The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif.

Zhang X, et al. (2005 May 27). The critical role of Exo84p in the organization and polarized localization of the exocyst complex.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%