FOG11254
EOG8QNKCT

sce:MFT1

Genes: 5

SGD Description
Subunit of the THO complex; THO is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance


References

Ito M, et al. (1993 Apr 5). Precise mapping and molecular characterization of the MFT1 gene involved in import of a fusion protein into mitochondria in Saccharomyces cerevisiae.

Chávez S, et al. (2000 Nov 1). A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.

Jimeno S, et al. (2002 Jul 1). The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Strässer K, et al. (2002 May 16). TREX is a conserved complex coupling transcription with messenger RNA export.

Rondón AG, et al. (2003 Oct 3). Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

Huertas P, et al. (2003 Sep). Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.

Abruzzi KC, et al. (2004 Jul 7). Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%