FOG11176
EOG8QV9W1

sce:BUB2

Genes: 30

SGD Description
Mitotic exit network regulator; forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage


PomBase Description
two-component GAP Cdc16


AspGD Description
Ortholog(s) have GTPase activator activity and role in cellular response to drug, hyphal growth, mitotic spindle assembly checkpoint, negative regulation of septation initiation signaling, positive regulation of GTPase activity


References

Hoyt MA, et al. (1991 Aug 9). S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function.

Lee SE, et al. (2001 Jun). The Bub2-dependent mitotic pathway in yeast acts every cell cycle and regulates cytokinesis.

Kim JM, et al. (2009 Jun). Timely septation requires SNAD-dependent spindle pole body localization of the septation initiation network components in the filamentous fungus Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%