FOG05337
EOG83R287

sce:SAP30

Genes: 28

SGD Description
Component of Rpd3L histone deacetylase complex; involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN6196, A. fumigatus Af293 : Afu2g11770, A. oryzae RIB40 : AO090026000469, Aspergillus wentii : Aspwe1_0031226 and Aspergillus sydowii : Aspsy1_0045308


References

Zhang Y, et al. (1998 Jun). SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex.

Sun ZW, et al. (1999 Jul). A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.

Nourani A, et al. (2003 May 23). Opposite role of yeast ING family members in p53-dependent transcriptional activation.

Carrozza MJ, et al. (2005 Nov 10). Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Keogh MC, et al. (2005 Nov 18). Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%