FOG05294
EOG8547H3

sce:ORC6

Genes: 24

SGD Description
Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p; mutation in the human Orc6p is linked to Meier-Gorlin syndrome


References

Li JJ, et al. (1993 Dec 17). Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system.

Asano T, et al. (2007 Dec). Interaction between ORC and Cdt1p of Saccharomyces cerevisiae.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Chen S, et al. (2007 Nov 15). Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 11 genes with posterior transmembrane prediction > 50%