FOG05060
EOG8BRV2X

sce:ACT1

Genes: 34

SGD Description
Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions


PomBase Description
actin Act1


AspGD Description
Actin structural protein


References

Clutterbuck AJ, et al. (1973 Jun). Gene symbols in Aspergillus nidulans.

Ng R, et al. (1980 Jul). Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

Gallwitz D, et al. (1980 Mar 11). Molecular cloning of the actin gene from yeast Saccharomyces cerevisiae.

Gallwitz D, et al. (1980 May). Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae.

Nellen W, et al. (1981). The nucleotide sequences of the actin genes from Saccharomyces carlsbergensis and Saccharomyces cerevisiae are identical except for their introns.

Domdey H, et al. (1984 Dec). Lariat structures are in vivo intermediates in yeast pre-mRNA splicing.

Fidel S, et al. (1988 Oct 30). Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a gamma-actin.

Deshler JO, et al. (1989 May). Kluyveromyces lactis maintains Saccharomyces cerevisiae intron-encoded splicing signals.

Johannes FJ, et al. (1991 Dec). Site-directed mutagenesis of the yeast actin gene: a test for actin function in vivo.

Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.

Cook RK, et al. (1991 Sep 5). Unusual metabolism of the yeast actin amino terminus.

Lee DW, et al. (1996 Apr 15). Quantitative analysis of gene expression in sexual structures of Aspergillus nidulans by sequencing of 3'-directed cDNA clones.

Norbeck J, et al. (1996 Mar 15). Protein expression during exponential growth in 0.7 M NaCl medium of Saccharomyces cerevisiae.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Maeting I, et al. (1999 Feb 5). Isocitrate lyase of Ashbya gossypii--transcriptional regulation and peroxisomal localization.

Daniel HM, et al. (2001 Jul). Partial sequence analysis of the actin gene and its potential for studying the phylogeny of Candida species and their teleomorphs.

Kang HA, et al. (2001 Jun). Molecular characterization of the actin-encoding gene and the use of its promoter for a dominant selection system in the methylotrophic yeast Hansenula polymorpha.

Kurtzman CP, et al. (2003 Jun). Phylogenetic relationships among yeasts of the 'Saccharomyces complex' determined from multigene sequence analyses.

Vorobiev S, et al. (2003 May 13). The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.

Daniel HM, et al. (2003 Sep 1). Evaluation of ribosomal RNA and actin gene sequences for the identification of ascomycetous yeasts.

Diezmann S, et al. (2004 Dec). Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis.

Sims AH, et al. (2004 Feb). Use of expressed sequence tag analysis and cDNA microarrays of the filamentous fungus Aspergillus nidulans.

Sattlegger E, et al. (2004 Jul 16). YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.

Upadhyay S, et al. (2008 May). The role of actin, fimbrin and endocytosis in growth of hyphae in Aspergillus nidulans.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Sato I, et al. (2009 Mar 20). The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

Schoustra S, et al. (2010 Aug 10). Fitness-associated sexual reproduction in a filamentous fungus.

Nahlik K, et al. (2010 Nov). The COP9 signalosome mediates transcriptional and metabolic response to hormones, oxidative stress protection and cell wall rearrangement during fungal development.

Sattlegger E, et al. (2011 Mar 25). Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Gerke J, et al. (2012 Jun). Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans.

Martins I, et al. (2013 Dec 6). Proteomic alterations induced by ionic liquids in Aspergillus nidulans and Neurospora crassa.

Ravin NV, et al. (2013 Nov 27). Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%

FOG05061
EOG8BRV2X

sce:ARP1

Genes: 24

SGD Description
Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin


AspGD Description
Ortholog(s) have role in conidiophore development, conidium formation, hyphal growth, nuclear migration along microtubule, regulation of growth rate and cytoplasmic dynein complex, hyphal tip localization


References

Muhua L, et al. (1994 Aug 26). A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration.

Clark SW, et al. (1994 Oct). ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle.

Kahana JA, et al. (1998 Jul). The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.

Xiang X, et al. (1999 Jul). Isolation of a new set of Aspergillus nidulans mutants defective in nuclear migration.

Xiang X, et al. (2000 May 18). Dynamics of cytoplasmic dynein in living cells and the effect of a mutation in the dynactin complex actin-related protein Arp1.

Hoffmann B, et al. (2001 Oct 19). The LIS1-related protein NUDF of Aspergillus nidulans and its interaction partner NUDE bind directly to specific subunits of dynein and dynactin and to alpha- and gamma-tubulin.

Maruyama J, et al. (2002 Jan 2). Observation of EGFP-visualized nuclei and distribution of vacuoles in Aspergillus oryzae arpA null mutant.

Zhang J, et al. (2003 Apr). Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependent.

Hoffmann B, et al. (2004 Jan 2). The LIS1-related protein NUDF of Aspergillus nidulans and its interaction partner NUDE bind directly to specific subunits of dynein and dynactin and to alpha- and gamma-tubulin.

Suzuki M, et al. (2004 Sep). Dynactin is involved in a checkpoint to monitor cell wall synthesis in Saccharomyces cerevisiae.

Igarashi R, et al. (2005). Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae.

Clark SW, et al. (2005 Sep). Alanine scanning of Arp1 delineates a putative binding site for Jnm1/dynamitin and Nip100/p150Glued.

Clark SW, et al. (2006 Feb). Arp10p is a pointed-end-associated component of yeast dynactin.

Zhuang L, et al. (2007 Mar). Point mutations in the stem region and the fourth AAA domain of cytoplasmic dynein heavy chain partially suppress the phenotype of NUDF/LIS1 loss in Aspergillus nidulans.

Zhang J, et al. (2008 Jul). Arp11 affects dynein-dynactin interaction and is essential for dynein function in Aspergillus nidulans.

Araújo-Bazán L, et al. (2008 Mar). NapA and NapB are the Aspergillus nidulans Nap/SET family members and NapB is a nuclear protein specifically interacting with importin alpha.

Zhang J, et al. (2011 Jun 27). The p25 subunit of the dynactin complex is required for dynein-early endosome interaction.

Egan MJ, et al. (2012 Dec). Microtubule-based transport in filamentous fungi.

Etxebeste O, et al. (2013). Cytoplasmic dynamics of the general nuclear import machinery in apically growing syncytial cells.

Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.

Egan MJ, et al. (2015 Apr 14). Cytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungi.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG05062
EOG8BRV2X

sce:absent

Genes: 6

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%