FOG05056
EOG8BRV3T

sce:PIL1;LSP1

Genes: 53

SGD Description
Eisosome core component; eisosomes are large immobile cell cortex structures associated with endocytosis; detected in phosphorylated state in mitochondria; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutant shows activation of Pkc1p/Ypk1p stress resistance pathways; member of BAR domain family; protein increases in abundance and relocalizes from plasma membrane to cytoplasm upon DNA replication stress|Eisosome core component; eisosomes are large immobile patch structures at the cell cortex associated with endocytosis; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; member of the BAR domain family


PomBase Description
eisosome BAR domain protein Pil1


AspGD Description
Ortholog(s) have lipid binding activity and role in eisosome assembly, endocytosis, negative regulation of protein kinase activity, protein localization, response to heat


References

Zhang X, et al. (2004 May 21). Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Walther TC, et al. (2006 Feb 23). Eisosomes mark static sites of endocytosis.

Reinders J, et al. (2007 Nov). Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.

Vangelatos I, et al. (2010 Oct). Eisosome organization in the filamentous ascomycete Aspergillus nidulans.

Scazzocchio C, et al. (2011 Jan). Eisosomes and membrane compartments in the ascomycetes: A view from Aspergillus nidulans.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Athanasopoulos A, et al. (2013 Apr). Eisosome distribution and localization in the meiotic progeny of Aspergillus nidulans.

Kollath-Leiß K, et al. (2014 Aug). BEM46 shows eisosomal localization and association with tryptophan-derived auxin pathway in Neurospora crassa.

Athanasopoulos A, et al. (2015 Oct 15). Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG05057
EOG8BRV3T

sce:absent

Genes: 3

AspGD Description
Ortholog of Aspergillus tubingensis : Asptu1_0124317, Aspergillus brasiliensis : Aspbr1_0025232 and Aspergillus kawachii : Aspka1_0174269


References

Vangelatos I, et al. (2010 Oct). Eisosome organization in the filamentous ascomycete Aspergillus nidulans.

Scazzocchio C, et al. (2011 Jan). Eisosomes and membrane compartments in the ascomycetes: A view from Aspergillus nidulans.

Athanasopoulos A, et al. (2013 Apr). Eisosome distribution and localization in the meiotic progeny of Aspergillus nidulans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG05058
EOG8BRV3T

sce:absent

Genes: 2

PomBase Description
meiotic eisosome BAR domain protein Pil2|sporulation specific PIL domain protein Meu14

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%