FOG04951
EOG8FN2ZK

sce:KEL2;KEL1

Genes: 34

SGD Description
Protein that negatively regulates mitotic exit; forms a complex with Kel1p and Bud14p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel1p, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate|Protein required for proper cell fusion and cell morphology; forms a complex with Bud14p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate


PomBase Description
cell end marker Tea1


AspGD Description
Ortholog(s) have role in apical protein localization, cellular protein localization and establishment or maintenance of cell polarity regulating cell shape, more


References

Philips J, et al. (1998 Oct 19). Identification of Kel1p, a kelch domain-containing protein involved in cell fusion and morphology in Saccharomyces cerevisiae.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Takeshita N, et al. (2008 Jan). Apical sterol-rich membranes are essential for localizing cell end markers that determine growth directionality in the filamentous fungus Aspergillus nidulans.

Fischer R, et al. (2008 May). Polarized growth in fungi--interplay between the cytoskeleton, positional markers and membrane domains.

Higashitsuji Y, et al. (2009 Jul). The cell end marker protein TeaC is involved in growth directionality and septation in Aspergillus nidulans.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Seiler S, et al. (2010 Dec). Conserved components, but distinct mechanisms for the placement and assembly of the cell division machinery in unicellular and filamentous ascomycetes.

Takeshita N, et al. (2011 Jun). On the role of microtubules, cell end markers, and septal microtubule organizing centres on site selection for polar growth in Aspergillus nidulans.

Takeshita N, et al. (2013 Dec 1). The cell-end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans to provide polarity maintenance.

Herrero S, et al. (2014 Aug). F-box protein RcyA controls turnover of the kinesin-7 motor KipA in Aspergillus nidulans.

Manck R, et al. (2015 Oct 1). Genetic evidence for a microtubule-capture mechanism during polarised growth of Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%