FOG04908
EOG8GMSHF

sce:HPC2

Genes: 20

SGD Description
Subunit of the HIR complex; HIR is a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes


References

Xu H, et al. (1992 Nov). Identification of a new set of cell cycle-regulatory genes that regulate S-phase transcription of histone genes in Saccharomyces cerevisiae.

Formosa T, et al. (2002 Dec). Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.

Prochasson P, et al. (2005 Nov 1). The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Green EM, et al. (2005 Nov 22). Replication-independent histone deposition by the HIR complex and Asf1.

Juneau K, et al. (2007 Jan 30). High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%