FOG04552
EOG8RN8S2

sce:SGO1

Genes: 11

SGD Description
Component of the spindle checkpoint; involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability; recruits condensin to the pericentric region of chromosomes during meiosis; dissociates from pericentromeres when sister kinetochores are under tension


References

Katis VL, et al. (2004 Apr 6). Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.

Marston AL, et al. (2004 Feb 27). A genome-wide screen identifies genes required for centromeric cohesion.

Indjeian VB, et al. (2005 Jan 7). The centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes.

Penkner AM, et al. (2005 Mar 25). Mnd2, an essential antagonist of the anaphase-promoting complex during meiotic prophase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%