FOG04458
EOG8THT8Q
sce:PEX5
Genes: 35
EOG8THT8Q
sce:PEX5
Genes: 35
SGD Description
Peroxisomal membrane signal receptor for peroxisomal matrix proteins; receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins; required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions
PomBase Description
peroxisomal targeting signal receptor Pex5
AspGD Description
Ortholog(s) have peroxisome matrix targeting signal-1 binding, protein binding, bridging activity and role in fatty acid beta-oxidation, penicillin biosynthetic process, protein import into peroxisome matrix, docking
References
Van der Leij I, et al. (1993 Dec 15). PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae.
Szilard RK, et al. (1995 Dec). Pay32p of the yeast Yarrowia lipolytica is an intraperoxisomal component of the matrix protein translocation machinery.
Navarro-García F, et al. (1998 Sep 15). Cloning and sequence of a 3.835 kbp DNA fragment containing the HIS4 gene and a fragment of a PEX5-like gene from Candida albicans.
Kiel JA, et al. (2006 Oct). PEX genes in fungal genomes: common, rare or redundant.
Williams C, et al. (2007 Aug 3). A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.
Hynes MJ, et al. (2008 Mar). Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans.
Jourdain I, et al. (2008 Mar). Dynamin-dependent biogenesis, cell cycle regulation and mitochondrial association of peroxisomes in fission yeast.
Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.
Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.
Spröte P, et al. (2009 Mar). Contribution of peroxisomes to penicillin biosynthesis in Aspergillus nidulans.
Reiser K, et al. (2010 Apr). AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for beta-oxidation in A. nidulans.
Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Magliano P, et al. (2011 Dec 9). Contributions of the peroxisome and β-oxidation cycle to biotin synthesis in fungi.
Gründlinger M, et al. (2013 Jun). Fungal siderophore biosynthesis is partially localized in peroxisomes.
Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.
Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.
Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
||
FOG04459
EOG8THT8Q
sce:absent
Genes: 18
EOG8THT8Q
sce:absent
Genes: 18
SGD Description
Protein of unknown function with low sequence identity to Pdc1p; mRNA identified as translated by ribosome profiling data
PomBase Description
2-hydroxyacyl-CoA lyase Hac1 (predicted)
AspGD Description
Ortholog(s) have cytosol localization
References
Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.
Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.
Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
||
FOG04460
EOG8THT8Q
sce:absent
Genes: 1
EOG8THT8Q
sce:absent
Genes: 1
SGD Description
Putative protein of unknown function with similarity to human PEX5Rp; transcription increases during colony development similar to genes involved in peroxisome biogenesis; YMR018W is not an essential gene; PEX5Rp is also known as peroxin protein 5 related protein
References
Ito T, et al. (2001 Apr 10). A comprehensive two-hybrid analysis to explore the yeast protein interactome.
Amery L, et al. (2001 Aug 1). Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
