FOG04421
EOG8VQ87V

sce:SAM35

Genes: 21

SGD Description
Component of the sorting and assembly machinery (SAM) complex; the SAM (or TOB) complex is located in the mitochondrial outer membrane; the complex binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane


References

Errede B, et al. (1989 Sep). STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.

Ishikawa D, et al. (2004 Aug 30). Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly.

Gentle I, et al. (2004 Jan 5). The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria.

Waizenegger T, et al. (2004 Jul). Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria.

Milenkovic D, et al. (2004 May 21). Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%