FOG04304
EOG8XKSRF

sce:VPS5

Genes: 36

SGD Description
Nexin-1 homolog; required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to late Golgi; structural component of retromer membrane coat complex; forms a retromer subcomplex with Vps17p; required for recruiting the retromer complex to the endosome membranes; VPS5 has a paralog, YKR078W, that arose from the whole genome duplication


PomBase Description
retromer complex subunit Vps5


AspGD Description
Ortholog(s) have phosphatidylinositol-3-phosphate binding, protein transporter activity


References

Horazdovsky BF, et al. (1997 Aug). A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor.

Nothwehr SF, et al. (1997 May). The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi.

Seaman MN, et al. (1998 Aug 10). A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04305
EOG8XKSRF

sce:absent

Genes: 6

AspGD Description
S-adenosylmethionine synthetase18364712

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04306
EOG8XKSRF

sce:absent

Genes: 2

SGD Description
Cytoplasmic protein of unknown function; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P); YKR078W has a paralog, VPS5, that arose from the whole genome duplication

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%