FOG04265
EOG8ZKH6J

sce:PSR2;PSR1

Genes: 37

SGD Description
Plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p; PSR2 has a paralog, PSR1, that arose from the whole genome duplication|Plasma membrane associated protein phosphatase; involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p; PSR1 has a paralog, PSR2, that arose from the whole genome duplication


PomBase Description
NLI interacting factor family phosphatase Psr1 (predicted)


AspGD Description
Ortholog(s) have role in regulation of spore germination


References

Siniossoglou S, et al. (2000 Jun 23). Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast.

Kaida D, et al. (2002 Jun). Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04266
EOG8ZKH6J

sce:TIM50

Genes: 33

SGD Description
Essential component of the TIM23 complex; acts as receptor for the translocase of the inner mitochondrial membrane (TIM23) complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel


PomBase Description
TIM23 translocase complex subunit Tim50 (predicted)


AspGD Description
Ortholog(s) have mitochondrion targeting sequence binding, protein channel activity


References

Geissler A, et al. (2002 Nov 15). The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel.

Yamamoto H, et al. (2002 Nov 15). Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.

Chacinska A, et al. (2003 Oct 15). Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex.

Chacinska A, et al. (2005 Mar 25). Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%

FOG04267
EOG8ZKH6J

sce:NEM1

Genes: 31

SGD Description
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard


PomBase Description
Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted)


AspGD Description
Has domain(s) with predicted phosphatase activity


References

Siniossoglou S, et al. (1998 Nov 16). A novel complex of membrane proteins required for formation of a spherical nucleus.

Santos-Rosa H, et al. (2005 Jun 1). The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth.

Son S, et al. (2009 Apr). Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1.

Jimenez J, et al. (2015 Dec). AnABlast: a new in silico strategy for the genome-wide search of novel genes and fossil regions.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 24 genes with posterior transmembrane prediction > 50%