FOG04264
EOG8ZKH7P

sce:TFB5

Genes: 28

SGD Description
Component of RNA polymerase II general transcription factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; relocalizes to the cytosol in response to hypoxia; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair


PomBase Description
transcription factor TFIIH complex subunit Tfb5 (predicted)


AspGD Description
Ortholog(s) have role in nucleotide-excision repair, phosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter and core TFIIH complex, cytosol, holo TFIIH complex localization


References

Svejstrup JQ, et al. (1994 Nov 11). RNA polymerase transcription factor IIH holoenzyme from yeast.

Sung P, et al. (1996 May 3). Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair.

Ranish JA, et al. (2004 Jul). Identification of TFB5, a new component of general transcription and DNA repair factor IIH.

Tallada VA, et al. (2007 May). Suppression of the Schizosaccharomyces pombe cut12.1 cell-cycle defect by mutations in cdc25 and genes involved in transcriptional and translational control.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%