FOG04158
EOG85DV71

sce:GET2

Genes: 13

SGD Description
Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division


References

Hughes TR, et al. (2000 Jul 7). Functional discovery via a compendium of expression profiles.

Ho Y, et al. (2002 Jan 10). Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.

Enyenihi AH, et al. (2003 Jan). Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae.

Zewail A, et al. (2003 Mar 18). Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin.

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Schuldiner M, et al. (2005 Nov 4). Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Auld KL, et al. (2006 Sep). The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Schuldiner M, et al. (2008 Aug 22). The GET complex mediates insertion of tail-anchored proteins into the ER membrane.

Stefer S, et al. (2011 Aug 5). Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex.

Wang F, et al. (2011 Sep 2). The mechanism of tail-anchored protein insertion into the ER membrane.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 12 genes with posterior transmembrane prediction > 50%