FOG04157
EOG85MKRF

sce:NNF1

Genes: 24

SGD Description
Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)


PomBase Description
NMS complex subunit Nnf1


AspGD Description
Ortholog(s) have role in chromosome segregation and NMS complex, nuclear MIS12/MIND complex localization


References

Shan X, et al. (1997 Jul). NNF1 is an essential yeast gene required for proper spindle orientation, nucleolar and nuclear envelope structure and mRNA export.

Euskirchen GM, et al. (2002 Apr). Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae.

De Wulf P, et al. (2003 Dec 1). Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.

Scharfenberger M, et al. (2003 Dec 15). Nsl1p is essential for the establishment of bipolarity and the localization of the Dam-Duo complex.

Pinsky BA, et al. (2003 Nov). An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Dimitrova YN, et al. (2016 Nov 3). Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%