FOG03963
EOG8K6DMH
sce:ALY1;ALY2
Genes: 37
EOG8K6DMH
sce:ALY1;ALY2
Genes: 37
SGD Description
Alpha arrestin, substrate of calcineurin; controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; dephosphorylation of Aly1p required for the endocytosis of Dip5p; may regulate endocytosis of plasma membrane proteins by recruiting ubiquitin ligase Rsp5p to plasma membrane targets; ALY1 has a paralog, ALY2, that arose from the whole genome duplication|Alpha arrestin; controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; phosphorylated by Npr1p and also by cyclin-CDK complex Pcl7p-Pho85p; promotes endocytosis of plasma membrane proteins; ALY2 has a paralog, ALY1, that arose from the whole genome duplication
PomBase Description
arrestin Aly1 related, implicated in endocytosis
AspGD Description
Ortholog(s) have ubiquitin protein ligase binding activity, role in endocytosis, positive regulation of ubiquitin-dependent endocytosis, regulation of intracellular transport and early endosome, late endosome localization
References
Shi XZ, et al. (2002 Jul). Analysis of phosphorylation of YJL084c, a yeast protein.
Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Gupta R, et al. (2007). Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.
Lin CH, et al. (2008 Nov 14). Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.
Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.
Duncan CD, et al. (2014 Jul). The translational landscape of fission-yeast meiosis and sporulation.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
||
FOG03964
EOG8K6DMH
sce:ECM21
Genes: 16
EOG8K6DMH
sce:ECM21
Genes: 16
SGD Description
Protein involved in regulating endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements; ECM21 has a paralog, CSR2, that arose from the whole genome duplication
References
Lussier M, et al. (1997 Oct). Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.
Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.
Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
FOG03965
EOG8K6DMH
sce:absent
Genes: 8
EOG8K6DMH
sce:absent
Genes: 8
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
||
FOG03966
EOG8K6DMH
sce:CSR2
Genes: 2
EOG8K6DMH
sce:CSR2
Genes: 2
SGD Description
Nuclear ubiquitin protein ligase binding protein; may regulate utilization of nonfermentable carbon sources and endocytosis of plasma membrane proteins; overproduction suppresses chs5 spa2 lethality at high temp; ubiquitinated by Rsp5p, deubiquitinated by Ubp2p; CSR2 has a paralog, ECM21, that arose from the whole genome duplication
AspGD Description
Ortholog of A. fumigatus Af293 : Afu5g10710, Neosartorya fischeri NRRL 181 : NFIA_076510, Aspergillus wentii : Aspwe1_0172590 and Aspergillus clavatus NRRL 1 : ACLA_013830
References
Santos B, et al. (2000 Feb). Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.
Kabir MA, et al. (2000 Jan). Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae.
Khanday FA, et al. (2002 Dec). Molecular characterization of MRG19 of Saccharomyces cerevisiae. Implication in the regulation of galactose and nonfermentable carbon source utilization.
Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.
Ubersax JA, et al. (2003 Oct 23). Targets of the cyclin-dependent kinase Cdk1.
Kharade SV, et al. (2005 Dec 19). Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence.
Das M, et al. (2005 Jan). Disruption of MRG19 results in altered nitrogen metabolic status and defective pseudohyphal development in Saccharomyces cerevisiae.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
