FOG03714
EOG80RXXH
EOG844J26

sce:CRZ1

Genes: 31

SGD Description
Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium


PomBase Description
calcineurin responsive transcription factor Prz1


AspGD Description
Ortholog(s) have sequence-specific DNA binding activity


References

Matheos DP, et al. (1997 Dec 15). Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae.

Stathopoulos-Gerontides A, et al. (1999 Apr 1). Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation.

Lan CY, et al. (2002 Nov 12). Metabolic specialization associated with phenotypic switching in Candidaalbicans.

Onyewu C, et al. (2004 Dec). The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans.

Santos M, et al. (2005 Aug). Functional characterization of the Candida albicans CRZ1 gene encoding a calcineurin-regulated transcription factor.

Cowen LE, et al. (2006 Dec). Genetic architecture of Hsp90-dependent drug resistance.

Sopko R, et al. (2006 Feb 3). Mapping pathways and phenotypes by systematic gene overexpression.

Karababa M, et al. (2006 Mar). CRZ1, a target of the calcineurin pathway in Candida albicans.

Fujioka T, et al. (2007 Aug). MpkA-Dependent and -independent cell wall integrity signaling in Aspergillus nidulans.

Hagiwara D, et al. (2008 Dec). Functional analysis of C2H2 zinc finger transcription factor CrzA involved in calcium signaling in Aspergillus nidulans.

Soriani FM, et al. (2008 Mar). Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Ramsdale M, et al. (2008 Oct). MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.

Spielvogel A, et al. (2008 Sep 15). Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Soriani FM, et al. (2010 Jan 15). Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Wang H, et al. (2011 Aug). Alkaline stress triggers an immediate calcium fluctuation in Candida albicans mediated by Rim101p and Crz1p transcription factors.

Gao L, et al. (2011 Nov). Osmotic stabilizer-coupled suppression of NDR defects is dependent on the calcium-calcineurin signaling cascade in Aspergillus nidulans.

Hernández-Ortiz P, et al. (2013 Aug). Phospho-regulation and nucleocytoplasmic trafficking of CrzA in response to calcium and alkaline-pH stress in Aspergillus nidulans.

Almeida RS, et al. (2013 Jul 8). Genetic bypass of Aspergillus nidulans crzA function in calcium homeostasis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03715
EOG80RXXH

sce:absent

Genes: 24

AspGD Description
Ortholog(s) have role in conidium formation, negative regulation of conidium formation and positive regulation of sexual sporulation resulting in formation of a cellular spore, more


References

Han KH, et al. (2001 Jul). The nsdD gene encodes a putative GATA-type transcription factor necessary for sexual development of Aspergillus nidulans.

Kim HR, et al. (2009 Jul). The nsdC gene encoding a putative C2H2-type transcription factor is a key activator of sexual development in Aspergillus nidulans.

Park HS, et al. (2012 Dec). Genetic control of asexual sporulation in filamentous fungi.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Garzia A, et al. (2013 Feb). Transcriptional changes in the transition from vegetative cells to asexual development in the model fungus Aspergillus nidulans.

Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.

Sun X, et al. (2013 May). PyrG is required for maintaining stable cellular uracil level and normal sporulation pattern under excess uracil stress in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03716
EOG80RXXH

sce:absent

Genes: 14

References

Bensen ES, et al. (2004 Dec). Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p.

Kullas AL, et al. (2007 Nov). Adaptation to environmental pH: integrating the Rim101 and calcineurin signal transduction pathways.

Ramsdale M, et al. (2008 Oct). MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.

Finkel JS, et al. (2012 Feb). Portrait of Candida albicans adherence regulators.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03717
EOG80RXXH
EOG859ZWH
EOG8QZ61T

sce:absent

Genes: 4

AspGD Description
Has domain(s) with predicted nucleic acid binding, zinc ion binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03718
EOG80RXXH

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%