FOG03489
EOG8S1RSF
EOG8TB2SW

sce:absent

Genes: 13

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03490
EOG8S1RSF

sce:absent

Genes: 8

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03491
EOG8S1RSF

sce:absent

Genes: 5

AspGD Description
Has domain(s) with predicted role in mRNA processing

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03492
EOG8S1RSF
EOG8TB2WS

sce:absent

Genes: 5

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03493
EOG8TB2SW

sce:SLX5

Genes: 5

SGD Description
Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by SUMO-modified substrates; contains a RING domain and two SIM motifs; forms SUMO-dependent nuclear foci, including DNA repair centers; associates with the centromere; null mutants are aneuploid, have a metaphase delay, and spindle defects including: mispositioned spindles, fish hook spindles, and aberrant spindle kinetics; required for maintenance of genome integrity like human ortholog RNF4


References

Mullen JR, et al. (2001 Jan). Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.

Wang Z, et al. (2006 Mar). Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae.

Zhang C, et al. (2006 Mar 7). Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae.

Ii T, et al. (2007 Nov). Stimulation of in vitro sumoylation by Slx5-Slx8: evidence for a functional interaction with the SUMO pathway.

Ii T, et al. (2007 Nov 15). The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity.

Xie Y, et al. (2007 Nov 23). The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation.

Burgess RC, et al. (2007 Sep). The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination.

Darst RP, et al. (2008 Feb). Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2.

Mullen JR, et al. (2008 Jul 18). Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates.

Nagai S, et al. (2008 Oct 24). Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03494
EOG8S1RSF

sce:absent

Genes: 1

PomBase Description
splicing factor Cwf7

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03495
EOG8TB2SW

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%