FOG03436
EOG81898N
sce:PZF1
Genes: 33
EOG81898N
sce:PZF1
Genes: 33
SGD Description
Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA
PomBase Description
RNA polymerase III transcription factor TFIIIA
AspGD Description
Ortholog(s) have cytosol, nucleus localization
References
Archambault J, et al. (1992 Feb 15). The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA.
Woychik NA, et al. (1992 May 1). Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae.
Schulman DB, et al. (2002 Jul 1). Identification and characterization of transcription factor IIIA from Schizosaccharomyces pombe.
Schulman DB, et al. (2003 Aug 8). Functional analysis of the novel C-terminal domains of S pombe transcription factor IIIA.
Singh RP, et al. (2011 Jul 15). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.
Nobile CJ, et al. (2012 Jan 20). A recently evolved transcriptional network controls biofilm development in Candida albicans.
Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03437
EOG81898N
sce:AZF1
Genes: 30
EOG81898N
sce:AZF1
Genes: 30
SGD Description
Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia
AspGD Description
Has domain(s) with predicted nucleic acid binding, zinc ion binding activity
References
Bröhl S, et al. (1994 Jun). A new nuclear suppressor system for a mitochondrial RNA polymerase mutant identifies an unusual zinc-finger protein and a polyglutamine domain protein in Saccharomyces cerevisiae.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03438
EOG81898N
sce:NRG1;NRG2
Genes: 27
EOG81898N
sce:NRG1;NRG2
Genes: 27
SGD Description
Transcriptional repressor; recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response; activated in stochastic pulses of nuclear localization in response to low glucose|Transcriptional repressor; mediates glucose repression and negatively regulates filamentous growth; activated in stochastic pulses of nuclear localization in response to low glucose
References
Murad AM, et al. (2001 Nov). Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1.
Braun BR, et al. (2001 Sep 3). NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction.
Murad AM, et al. (2001 Sep 3). NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans.
Nantel A, et al. (2002 Oct). Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.
Saville SP, et al. (2003 Oct). Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during infection.
Zheng XD, et al. (2003 Sep). CaSPA2 is important for polarity establishment and maintenance in Candida albicans.
Bensen ES, et al. (2004 Dec). Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p.
Toyoda M, et al. (2004 Dec). Transcriptional profiling of the early stages of germination in Candida albicans by real-time RT-PCR.
Lotz H, et al. (2004 Jun). RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.
Russell CL, et al. (2005 Aug). Expression of one-hybrid fusions with Staphylococcus aureus lexA in Candida albicans confirms that Nrg1 is a transcriptional repressor and that Gcn4 is a transcriptional activator.
Staib P, et al. (2005 Jan). Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis.
Chamilos G, et al. (2006 Apr 1). Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species.
Umeyama T, et al. (2006 May). Repression of CDC28 reduces the expression of the morphology-related transcription factors, Efg1p, Nrg1p, Rbf1p, Rim101p, Fkh2p and Tec1p and induces cell elongation in Candida albicans.
Saville SP, et al. (2006 Oct). Inhibition of filamentation can be used to treat disseminated candidiasis.
Banerjee M, et al. (2008 Apr). UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence.
Saville SP, et al. (2008 Jan). Use of a genetically engineered strain to evaluate the pathogenic potential of yeast cell and filamentous forms during Candida albicans systemic infection in immunodeficient mice.
Nobile CJ, et al. (2008 Nov). Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions.
Ramsdale M, et al. (2008 Oct). MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.
Saville SP, et al. (2009 Mar). Efficacy of a genetically engineered Candida albicans tet-NRG1 strain as an experimental live attenuated vaccine against hematogenously disseminated candidiasis.
Cleary IA, et al. (2010 Jul). An analysis of the impact of NRG1 overexpression on the Candida albicans response to specific environmental stimuli.
Uppuluri P, et al. (2010 Oct). The transcriptional regulator Nrg1p controls Candida albicans biofilm formation and dispersion.
Oh S, et al. (2012 Sep). The bacterial signalling molecule indole attenuates the virulence of the fungal pathogen Candida albicans.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03439
EOG81898N
EOG8QNKCV
sce:absent
Genes: 16
EOG81898N
EOG8QNKCV
sce:absent
Genes: 16
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03440
EOG81898N
sce:absent
Genes: 4
EOG81898N
sce:absent
Genes: 4
AspGD Description
Putative C2H2 transcription factor; predicted role in conidiation; expressed in germinating conidia
References
Wieser J, et al. (1994 Dec). Genetic requirements for initiating asexual development in Aspergillus nidulans.
Wieser J, et al. (1995 Feb 15). flbD encodes a Myb-like DNA-binding protein that coordinates initiation of Aspergillus nidulans conidiophore development.
Marhoul JF, et al. (1996 Dec). Aspergillus fabM encodes an essential product that is related to poly(A)-binding proteins and activates development when overexpressed.
Lee BN, et al. (1996 Jan 15). FluG and flbA function interdependently to initiate conidiophore development in Aspergillus nidulans through brlA beta activation.
Adams TH, et al. (1998 Dec). Coordinate control of secondary metabolite production and asexual sporulation in Aspergillus nidulans.
Adams TH, et al. (1998 Mar). Asexual sporulation in Aspergillus nidulans.
Han S, et al. (2001 Oct). Complex control of the developmental regulatory locus brlA in Aspergillus nidulans.
Kellner EM, et al. (2002 Jan). Mutations in sfdA and sfdB suppress multiple developmental mutations in Aspergillus nidulans.
Emri T, et al. (2005 Jul). The fluG-BrlA pathway contributes to the initialisation of autolysis in submerged Aspergillus nidulans cultures.
Seo JA, et al. (2006 Mar). FluG-dependent asexual development in Aspergillus nidulans occurs via derepression.
Yu JH, et al. (2006 Oct). Growth and developmental control in the model and pathogenic aspergilli.
Emri T, et al. (2008 Dec). Regulation of autolysis in Aspergillus nidulans.
Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.
Harris SD, et al. (2009 Sep). The Spitzenkörper: a signalling hub for the control of fungal development?
Kwon NJ, et al. (2010 Dec). Characterization of the developmental regulator FlbE in Aspergillus fumigatus and Aspergillus nidulans.
Ogawa M, et al. (2010 Jan). Genetic analysis of conidiation regulatory pathways in koji-mold Aspergillus oryzae.
Kwon NJ, et al. (2010 Sep). FlbC is a putative nuclear C2H2 transcription factor regulating development in Aspergillus nidulans.
Herrero-Garcia E, et al. (2011 Apr-May). 8-Carbon oxylipins inhibit germination and growth, and stimulate aerial conidiation in Aspergillus nidulans.
Ruger-Herreros C, et al. (2011 Aug). Regulation of conidiation by light in Aspergillus nidulans.
Park HS, et al. (2012 Dec). Genetic control of asexual sporulation in filamentous fungi.
Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.
Arratia-Quijada J, et al. (2012 Sep). FlbD, a Myb transcription factor of Aspergillus nidulans, is uniquely involved in both asexual and sexual differentiation.
Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.
Cánovas D, et al. (2014 Aug). The histone acetyltransferase GcnE (GCN5) plays a central role in the regulation of Aspergillus asexual development.
Malapi-Wight M, et al. (2014 Jan). The N-terminus region of the putative C2H2 transcription factor Ada1 harbors a species-specific activation motif that regulates asexual reproduction in Fusarium verticillioides.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03441
EOG81898N
sce:absent
Genes: 12
EOG81898N
sce:absent
Genes: 12
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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