FOG03423
EOG84B8H3

sce:TYE7

Genes: 13

SGD Description
Serine-rich protein that contains a bHLH DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression; bHLH stands for basic-helix-loop-helix


References

Löhning C, et al. (1994 Oct). The TYE7 gene of Saccharomyces cerevisiae encodes a putative bHLH-LZ transcription factor required for Ty1-mediated gene expression.

Nishi K, et al. (1995 May). The GCR1 requirement for yeast glycolytic gene expression is suppressed by dominant mutations in the SGC1 gene, which encodes a novel basic-helix-loop-helix protein.

Sato T, et al. (1999 Dec 17). The E-box DNA binding protein Sgc1p suppresses the gcr2 mutation, which is involved in transcriptional activation of glycolytic genes in Saccharomyces cerevisiae.

Nantel A, et al. (2002 Oct). Transcription profiling of Candida albicans cells undergoing the yeast-to-hyphal transition.

Barker KS, et al. (2004 Aug). Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.

Karababa M, et al. (2004 Aug). Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters.

Zhao R, et al. (2005 Jul). Unique aspects of gene expression during Candida albicans mating and possible G(1) dependency.

Liu TT, et al. (2005 Jun). Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans.

Sexton JA, et al. (2007 Oct). Regulation of sugar transport and metabolism by the Candida albicans Rgt1 transcriptional repressor.

Askew C, et al. (2009 Oct). Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Bonhomme J, et al. (2011 May). Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03424
EOG84B8H3

sce:absent

Genes: 10

PomBase Description
sterol regulatory element binding protein, transcription factor Sre1


AspGD Description
Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding, sterol response element binding and transcriptional activator activity, more

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%

FOG03425
EOG84B8H3

sce:absent

Genes: 5

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG03426
EOG84B8H3

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03427
EOG84B8H3

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03428
EOG84B8H3

sce:HMS1

Genes: 9

SGD Description
bHLH protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant


PomBase Description
membrane-tethered transcription factor Sre2


AspGD Description
Ortholog(s) have role in cellular response to hypoxia, pathogenesis and nucleus localization


References

Lorenz MC, et al. (1998 Dec). Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains.

Mach KE, et al. (1998 Sep). ras1 and pat1 alleles interact to quantitatively and qualitatively alter conjugation in fission yeast.

Keniry ME, et al. (2004 Mar). The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.

Calvo IA, et al. (2009 Aug 12). Genome-wide screen of genes required for caffeine tolerance in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Kwon EJ, et al. (2012). Deciphering the transcriptional-regulatory network of flocculation in Schizosaccharomyces pombe.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Cheung R, et al. (2013 Jul 12). Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.

Lloyd SJ, et al. (2013 Jul 19). Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.

Chen JS, et al. (2013 May). Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Hwang J, et al. (2016 Nov 2). A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Burr R, et al. (2017 Mar 31). Coordinate Regulation of Yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 Transcription Factors.

Burr R, et al. (2017 Sep 29). Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%