FOG03350
EOG8KSN0Z
sce:MCM5
Genes: 34
EOG8KSN0Z
sce:MCM5
Genes: 34
SGD Description
Component of the Mcm2-7 hexameric helicase complex; MCM complex is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
PomBase Description
MCM complex subunit Mcm5
AspGD Description
Ortholog(s) have role in negative regulation of helicase activity and MCM complex, cytosol, nucleus localization
References
Hennessy KM, et al. (1991 Jun). A group of interacting yeast DNA replication genes.
Chen Y, et al. (1992 Nov 1). CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences.
Miyake S, et al. (1993 Oct). Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family.
Okishio N, et al. (1996 Feb). Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins.
Adachi Y, et al. (1997 Jul). A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.
Forsburg SL, et al. (1997 Nov). Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.
Brown GW, et al. (1998 Aug 21). Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.
Sherman DA, et al. (1998 Jul). Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex.
Miyake S, et al. (1998 Mar). Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe.
Sherman DA, et al. (1998 Sep 1). Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p).
Liang DT, et al. (1999 Feb). Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay.
Forsburg SL, et al. (2000 Jul). Mitotic replication initiation proteins are not required for pre-meiotic S phase.
Lee JK, et al. (2000 Jun 23). Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.
Liang DT, et al. (2001 Oct). Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.
Gómez EB, et al. (2002 Apr). Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
Hart EA, et al. (2002 Aug). Fission yeast Cdc23 interactions with DNA replication initiation proteins.
Wysocka M, et al. (2004 Apr 1). Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.
Yamada Y, et al. (2004 Aug). A novel intermediate in initiation complex assembly for fission yeast DNA replication.
Forsburg SL, et al. (2004 Mar). Eukaryotic MCM proteins: beyond replication initiation.
Yuasa T, et al. (2004 Nov). An interactive gene network for securin-separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation.
Nitani N, et al. (2006 Sep). Regulation of DNA replication machinery by Mrc1 in fission yeast.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Li JJ, et al. (2011 Dec 15). Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex.
Santosa V, et al. (2013 Mar 8). The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
McDonald KR, et al. (2016 Sep). Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG03351
EOG8KSN0Z
sce:MCM2
Genes: 34
EOG8KSN0Z
sce:MCM2
Genes: 34
SGD Description
Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress
PomBase Description
MCM complex subunit Mcm2
AspGD Description
Ortholog(s) have DNA replication origin binding, chromatin binding, single-stranded DNA binding, single-stranded DNA-dependent ATP-dependent DNA helicase activity
References
Morris NR, et al. (1975 Dec). Mitotic mutants of Aspergillus nidulans.
Yan H, et al. (1991 Jun). Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.
Van Dyck L, et al. (1994 Jan 7). PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae.
James SW, et al. (1995 Nov). The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis.
Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.
Osmani SA, et al. (2004 Apr). The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans.
Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG03352
EOG8KSN0Z
sce:MCM6
Genes: 34
EOG8KSN0Z
sce:MCM6
Genes: 34
SGD Description
Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; forms a subcomplex with Mcm4p and Mcm7p
PomBase Description
MCM complex subunit Mcm6
AspGD Description
Ortholog(s) have ATP-dependent 3'-5' DNA helicase activity, ATP-dependent four-way junction helicase activity, DNA replication origin binding and single-stranded DNA binding, more
References
Merchant AM, et al. (1997 Jun). A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.
Iraqui I, et al. (1998 Jan). Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03353
EOG8KSN0Z
sce:MCM4
Genes: 33
EOG8KSN0Z
sce:MCM4
Genes: 33
SGD Description
Essential helicase component of heterohexameric MCM2-7 complexes; MCM2-7 complexes bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p
PomBase Description
MCM complex subunit Mcm4/Cdc21
AspGD Description
Ortholog(s) have ATP-dependent 3'-5' DNA helicase activity, ATP-dependent four-way junction helicase activity, DNA replication origin binding, chromatin binding and single-stranded DNA binding, more
References
Nasmyth K, et al. (1981). Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe.
Grallert B, et al. (1991 Aug). Common genes and pathways in the regulation of the mitotic and meiotic cell cycles of Schizosaccharomyces pombe.
Coxon A, et al. (1992 Nov 11). Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication.
Saka Y, et al. (1994 Nov 15). Fission yeast cut5 links nuclear chromatin and M phase regulator in the replication checkpoint control.
Forsburg SL, et al. (1994 Oct). The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins.
Takahashi K, et al. (1994 Oct). Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.
Maiorano D, et al. (1996 Feb 15). Fission yeast cdc21, a member of the MCM protein family, is required for onset of S phase and is located in the nucleus throughout the cell cycle.
Grallert B, et al. (1996 Oct 15). The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase.
Adachi Y, et al. (1997 Jul). A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.
Forsburg SL, et al. (1997 Nov). Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.
Brown GW, et al. (1998 Aug 21). Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.
Sherman DA, et al. (1998 Jul). Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex.
Pasion SG, et al. (1999 Dec). Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly.
Liang DT, et al. (1999 Feb). Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay.
Tanaka H, et al. (1999 Feb). Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.
Snaith HA, et al. (1999 Jul). Rereplication phenomenon in fission yeast requires MCM proteins and other S phase genes.
Grallert B, et al. (2000 Apr). A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls.
Kearsey SE, et al. (2000 Apr 3). Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18.
Nishitani H, et al. (2000 Apr 6). The Cdt1 protein is required to license DNA for replication in fission yeast.
Forsburg SL, et al. (2000 Jul). Mitotic replication initiation proteins are not required for pre-meiotic S phase.
Lee JK, et al. (2000 Jun 23). Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.
Griffiths D, et al. (2000 Mar). A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints.
Uchiyama M, et al. (2001 Aug). Sna41goa1, a novel mutation causing G1/S arrest in fission yeast, is defective in a CDC45 homolog and interacts genetically with polalpha.
Lee JK, et al. (2001 Jan 2). Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures.
Takeda T, et al. (2001 May). Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.
Liang DT, et al. (2001 Oct). Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.
Yanow SK, et al. (2001 Sep 3). Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication.
Gómez EB, et al. (2002 Apr). Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
Hart EA, et al. (2002 Aug). Fission yeast Cdc23 interactions with DNA replication initiation proteins.
Lindner K, et al. (2002 Feb). Essential role of MCM proteins in premeiotic DNA replication.
Wuarin J, et al. (2002 Nov 1). Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication.
Shin JH, et al. (2003 Dec 5). Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases.
Lee JK, et al. (2003 Mar 4). The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase.
Gregan J, et al. (2003 Sep). Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.
Spiga MG, et al. (2004). Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.
Dolan WP, et al. (2004 Sep). Schizosaccharomyces pombe replication protein Cdc45/Sna41 requires Hsk1/Cdc7 and Rad4/Cut5 for chromatin binding.
Locovei AM, et al. (2006 Nov 17). The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast.
Namdar M, et al. (2006 Oct 15). Analysis of Mcm2-7 chromatin binding during anaphase and in the transition to quiescence in fission yeast.
Shin JH, et al. (2006 Sep 15). The replicative helicases of bacteria, archaea, and eukarya can unwind RNA-DNA hybrid substrates.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Gómez EB, et al. (2008 Jun). Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation.
Bailis JM, et al. (2008 Mar). Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability.
Yin L, et al. (2008 Oct). Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation.
Nitani N, et al. (2008 Sep 2). Mcm4 C-terminal domain of MCM helicase prevents excessive formation of single-stranded DNA at stalled replication forks.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Akman G, et al. (2009 Feb 19). MCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeast.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Locovei AM, et al. (2010 Aug 27). A genetic screen for replication initiation defective (rid) mutants in Schizosaccharomyces pombe.
Li JJ, et al. (2011 Dec 15). Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex.
Maki K, et al. (2011 Dec 2). Abundance of prereplicative complexes (Pre-RCs) facilitates recombinational repair under replication stress in fission yeast.
Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.
Taylor M, et al. (2011 Nov 10). Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1).
Ding L, et al. (2011 Sep 23). Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase.
Sabatinos SA, et al. (2012 Dec). Continued DNA synthesis in replication checkpoint mutants leads to fork collapse.
Kanke M, et al. (2012 May 2). Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components.
Roseaulin LC, et al. (2013). Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complex.
Xu M, et al. (2013 Feb 27). Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7.
Santosa V, et al. (2013 Mar 8). The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.
Ranatunga NS, et al. (2016 Oct 13). Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4.
McDonald KR, et al. (2016 Sep). Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
Daigaku Y, et al. (2017 May). PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50% |
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FOG03354
EOG8KSN0Z
sce:MCM7
Genes: 33
EOG8KSN0Z
sce:MCM7
Genes: 33
SGD Description
Component of the Mcm2-7 hexameric helicase complex; MCM2-7 primes origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation in S-phase; forms an Mcm4p-6p-7p subcomplex
PomBase Description
MCM complex subunit Mcm7
AspGD Description
Ortholog(s) have ATP-dependent 3'-5' DNA helicase activity, single-stranded DNA binding, single-stranded DNA-dependent ATP-dependent DNA helicase activity and MCM complex, MCM core complex, nuclear chromatin localization
References
Dalton S, et al. (1995 Mar 28). Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.
Adachi Y, et al. (1997 Jul). A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.
Merchant AM, et al. (1997 Jun). A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.
Brown GW, et al. (1998 Aug 21). Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.
Lee JK, et al. (2000 Jun 23). Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.
Lee JK, et al. (2001 Jan 2). Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures.
Liang DT, et al. (2001 Oct). Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.
Gómez EB, et al. (2002 Apr). Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
Lindner K, et al. (2002 Feb). Essential role of MCM proteins in premeiotic DNA replication.
Nakajima R, et al. (2002 May). SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast.
Shin JH, et al. (2003 Dec 5). Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases.
Gregan J, et al. (2003 Sep). Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.
Wysocka M, et al. (2004 Apr 1). Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.
Yamada Y, et al. (2004 Aug). A novel intermediate in initiation complex assembly for fission yeast DNA replication.
Forsburg SL, et al. (2004 Mar). Eukaryotic MCM proteins: beyond replication initiation.
Dolan WP, et al. (2004 Sep). Schizosaccharomyces pombe replication protein Cdc45/Sna41 requires Hsk1/Cdc7 and Rad4/Cut5 for chromatin binding.
Namdar M, et al. (2006 Oct 15). Analysis of Mcm2-7 chromatin binding during anaphase and in the transition to quiescence in fission yeast.
Shin JH, et al. (2006 Sep 15). The replicative helicases of bacteria, archaea, and eukarya can unwind RNA-DNA hybrid substrates.
Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Gómez EB, et al. (2008 Jun). Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation.
Bailis JM, et al. (2008 Mar). Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Li JJ, et al. (2011 Dec 15). Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex.
Ding L, et al. (2011 Sep 23). Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase.
Xu M, et al. (2013 Feb 27). Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7.
Santosa V, et al. (2013 Mar 8). The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
McDonald KR, et al. (2016 Sep). Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03355
EOG8KSN0Z
sce:MCM3
Genes: 32
EOG8KSN0Z
sce:MCM3
Genes: 32
SGD Description
Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex
PomBase Description
MCM complex subunit Mcm3
AspGD Description
Ortholog(s) have role in negative regulation of helicase activity and MCM complex, cytosol, nuclear chromatin localization
References
Gibson SI, et al. (1990 Nov). The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.
Adachi Y, et al. (1997 Jul). A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast.
Brown GW, et al. (1998 Aug 21). Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.
Sherman DA, et al. (1998 Sep 1). Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p).
Pasion SG, et al. (1999 Dec). Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly.
Forsburg SL, et al. (2000 Jul). Mitotic replication initiation proteins are not required for pre-meiotic S phase.
Lee JK, et al. (2000 Jun 23). Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.
Liang DT, et al. (2001 Oct). Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.
Gómez EB, et al. (2002 Apr). Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.
Lee JK, et al. (2003 Mar 4). The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase.
Wysocka M, et al. (2004 Apr 1). Saccharomyces cerevisiae CSM1 gene encoding a protein influencing chromosome segregation in meiosis I interacts with elements of the DNA replication complex.
Dolan WP, et al. (2004 Sep). Schizosaccharomyces pombe replication protein Cdc45/Sna41 requires Hsk1/Cdc7 and Rad4/Cut5 for chromatin binding.
Namdar M, et al. (2006 Oct 15). Analysis of Mcm2-7 chromatin binding during anaphase and in the transition to quiescence in fission yeast.
Tafforeau L, et al. (2006 Oct 4). Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.
Bochman ML, et al. (2008 Jul 25). The Mcm2-7 complex has in vitro helicase activity.
Evrin C, et al. (2009 Dec 1). A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
Remus D, et al. (2009 Nov 13). Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Li JJ, et al. (2011 Dec 15). Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex.
Ding L, et al. (2011 Sep 23). Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase.
Santosa V, et al. (2013 Mar 8). The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.
Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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