FOG03332
EOG8NGF75

sce:HRB1;GBP2

Genes: 33

SGD Description
Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; HRB1 has a paralog, GBP2, that arose from the whole genome duplication|Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; also binds single-stranded telomeric repeat sequence in vitro; relocalizes to the cytosol in response to hypoxia; GBP2 has a paralog, HRB1, that arose from the whole genome duplication


PomBase Description
RNA-binding protein involved in export of mRNAs (predicted)


AspGD Description
Ortholog(s) have role in positive regulation of mitotic cell cycle and cytosol, nucleus localization


References

Lalo D, et al. (1993). Two yeast chromosomes are related by a fossil duplication of their centromeric regions.

Lalo D, et al. (1994 Apr). Organization of the centromeric region of chromosome XIV in Saccharomyces cerevisiae.

Lin JJ, et al. (1994 Nov 25). Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro.

Konkel LM, et al. (1995 Jun 6). A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei.

Pang TL, et al. (2003 Mar 14). Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae.

Zhang Z, et al. (2007 Apr). Genome-wide identification of spliced introns using a tiling microarray.

Juneau K, et al. (2007 Jan 30). High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Sugiyama T, et al. (2013 Jul). Red5 and three nuclear pore components are essential for efficient suppression of specific mRNAs during vegetative growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03333
EOG8NGF75

sce:NSR1

Genes: 31

SGD Description
Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis


PomBase Description
nucleolar protein required for rRNA processing


AspGD Description
Putative RNA-binding protein


References

Lee WC, et al. (1991 Apr). The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.

Kondo K, et al. (1992 Aug 15). Yeast NSR1 protein that has structural similarity to mammalian nucleolin is involved in pre-rRNA processing.

Lin JJ, et al. (1994 Nov 25). Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro.

Xu C, et al. (2003 Jun). In vivo analysis of nucleolar proteins modified by the yeast arginine methyltransferase Hmt1/Rmt1p.

Fedorova ND, et al. (2005 Dec 8). Comparative analysis of programmed cell death pathways in filamentous fungi.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03334
EOG8NGF75

sce:PRP24

Genes: 30

SGD Description
Splicing factor that reanneals snRNPs during spliceosome recycling; reanneals U4 and U6 snRNPs


PomBase Description
RNA-binding protein Prp24


AspGD Description
Ortholog(s) have nucleus localization


References

Shannon KW, et al. (1991 May). Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs.

Ghetti A, et al. (1995 Apr). Specificity of Prp24 binding to RNA: a role for Prp24 in the dynamic interaction of U4 and U6 snRNAs.

Jandrositz A, et al. (1995 Feb 15). Evidence for a Prp24 binding site in U6 snRNA and in a putative intermediate in the annealing of U6 and U4 snRNAs.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03335
EOG8NGF75

sce:absent

Genes: 10

PomBase Description
RNA-binding protein Rsd1 (predicted)


AspGD Description
Ortholog(s) have U1 snRNP binding activity, role in ascospore formation, sporocarp development involved in sexual reproduction and nucleus localization


References

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Shao W, et al. (2012 Jan). A U1-U2 snRNP interaction network during intron definition.

Tang Z, et al. (2012 Oct 1). Interacting factors and cellular localization of SR protein-specific kinase Dsk1.

Livesay SB, et al. (2013 Nov). Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.

Kallgren SP, et al. (2014). The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03336
EOG8NGF75

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted nucleic acid binding, nucleotide binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03337
EOG8NGF75

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%