FOG03245
EOG85HQD5
EOG870RZF
EOG8KD526
sce:BUL1;BUL2
Genes: 31
EOG85HQD5
EOG870RZF
EOG8KD526
sce:BUL1;BUL2
Genes: 31
SGD Description
Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex; disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases; BUL1 has a paralog, BUL2, that arose from the whole genome duplication|Component of the Rsp5p E3-ubiquitin ligase complex; involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions; BUL2 has a paralog, BUL1, that arose from the whole genome duplication
References
Yashiroda H, et al. (1996 Jul). Bul1, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae.
Yashiroda H, et al. (1998 Dec 28). The PY-motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions.
Andoh T, et al. (2000 Sep). Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5.
Helliwell SB, et al. (2001 May 14). Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.
Soetens O, et al. (2001 Nov 23). Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1.
Kaida D, et al. (2003 Jul 11). Rsp5-Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast.
Abe F, et al. (2003 Nov). Pressure-induced differential regulation of the two tryptophan permeases Tat1 and Tat2 by ubiquitin ligase Rsp5 and its binding proteins, Bul1 and Bul2.
Welsch CA, et al. (2004 Aug 27). Genetic, biochemical, and transcriptional responses of Saccharomyces cerevisiae to the novel immunomodulator FTY720 largely mimic those of the natural sphingolipid phytosphingosine.
Pizzirusso M, et al. (2004 May). Ubiquitin-mediated targeting of a mutant plasma membrane ATPase, Pma1-7, to the endosomal/vacuolar system in yeast.
Crespo JL, et al. (2004 Sep 3). NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.
Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Feller A, et al. (2006 Sep 29). Transduction of the nitrogen signal activating Gln3-mediated transcription is independent of Npr1 kinase and Rsp5-Bul1/2 ubiquitin ligase in Saccharomyces cerevisiae.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG03246
EOG870RZF
sce:BSC5
Genes: 9
EOG870RZF
sce:BSC5
Genes: 9
SGD Description
Protein of unknown function; shows homology with N-terminal end of Bul1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough expression includes YNR068C and the locus for this readthrough is termed BUL3; Bul3p is involved in ubiquitin-mediated sorting of plasma membrane proteins; readthrough and shortened forms of Bul3p interact with Rsp5p differently in vitro
References
Namy O, et al. (2003 May 1). Identification of stop codon readthrough genes in Saccharomyces cerevisiae.
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0 genes with posterior transmembrane prediction > 50% |
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FOG03247
EOG85HQD5
sce:absent
Genes: 5
EOG85HQD5
sce:absent
Genes: 5
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0 genes with posterior transmembrane prediction > 50% |
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FOG03248
EOG85HQD5
sce:absent
Genes: 5
EOG85HQD5
sce:absent
Genes: 5
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0 genes with posterior transmembrane prediction > 50% |
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FOG03249
EOG85HQD5
sce:absent
Genes: 4
EOG85HQD5
sce:absent
Genes: 4
AspGD Description
Ortholog of A. nidulans FGSC A4 : AN5453/artG, A. fumigatus Af293 : Afu6g13380, A. oryzae RIB40 : AO090003000465, Aspergillus wentii : Aspwe1_0047105 and Aspergillus sydowii : Aspsy1_0044061
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03250
EOG85HQD5
sce:absent
Genes: 3
EOG85HQD5
sce:absent
Genes: 3
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0 genes with posterior transmembrane prediction > 50% |
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FOG03251
EOG85HQD5
sce:absent
Genes: 2
EOG85HQD5
sce:absent
Genes: 2
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0 genes with posterior transmembrane prediction > 50% |
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FOG03252
EOG870RZF
sce:absent
Genes: 1
EOG870RZF
sce:absent
Genes: 1
SGD Description
Putative protein of unknown function; exhibits homology to C-terminal end of Bul1p; expressed as a readthrough product of BSC5, the readthrough locus being termed BUL3; the BUL3 readthrough product is involved in ubiquitin-mediated sorting of plasma membrane proteins and interacts with WW domains of Rsp5p in vitro, but in a functionally different way than the non-readthrough form
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03253
EOG8KD526
sce:absent
Genes: 1
EOG8KD526
sce:absent
Genes: 1
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03254
EOG85HQD5
sce:absent
Genes: 7
EOG85HQD5
sce:absent
Genes: 7
AspGD Description
Ortholog of Aspergillus tubingensis : Asptu1_0076679, Aspergillus brasiliensis : Aspbr1_0113784, Aspergillus kawachii : Aspka1_0176143 and Aspergillus acidus : Aspfo1_0126479|Ortholog of A. oryzae RIB40 : AO090038000101, Aspergillus tubingensis : Asptu1_0079832, Aspergillus brasiliensis : Aspbr1_0128603 and Aspergillus kawachii : Aspka1_0182791
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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