FOG03237
EOG89W0W6

sce:SEC7

Genes: 36

SGD Description
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles


PomBase Description
Sec7 domain protein, ARF GEF (predicted)|Sec7 domain protein, ARF GEF Sec72


AspGD Description
Putative guanine nucleotide exchange factor; expression enhanced by maltose


References

Achstetter T, et al. (1988 Aug 25). SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

Franzusoff A, et al. (1991 Jan). Localization of components involved in protein transport and processing through the yeast Golgi apparatus.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Vjestica A, et al. (2008 Mar). The actomyosin ring recruits early secretory compartments to the division site in fission yeast.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 20 genes with posterior transmembrane prediction > 50%

FOG03238
EOG89W0W6

sce:GEA1;GEA2

Genes: 34

SGD Description
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication|Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA2 has a paralog, GEA1, that arose from the whole genome duplication


PomBase Description
guanyl-nucleotide exchange factor (predicted)


AspGD Description
Putative guanine nucleotide exchange factor; expression enhanced by maltose


References

Peyroche A, et al. (1996 Dec 5). Nucleotide exchange on ARF mediated by yeast Gea1 protein.

Renault L, et al. (2002 Mar 19). Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.

Chantalat S, et al. (2003 Jun). A novel Golgi membrane protein is a partner of the ARF exchange factors Gea1p and Gea2p.

Deng Y, et al. (2009 Jan). A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 20 genes with posterior transmembrane prediction > 50%

FOG03239
EOG89W0W6

sce:absent

Genes: 20

PomBase Description
guanyl-nucleotide exchange factor Sec73 (predicted)|guanyl-nucleotide exchange factor Sec74 (predicted)


AspGD Description
Has domain(s) with predicted ARF guanyl-nucleotide exchange factor activity, phospholipid binding activity and role in regulation of ARF protein signal transduction


References

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 9 genes with posterior transmembrane prediction > 50%

FOG03240
EOG89W0W6
EOG8PC89S

sce:absent

Genes: 15

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03241
EOG89W0W6

sce:absent

Genes: 8

AspGD Description
Ortholog(s) have role in activation of bipolar cell growth and cell cortex of cell tip localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03242
EOG84QRH9
EOG8PC89S

sce:YEL1

Genes: 7

SGD Description
Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip


References

Gillingham AK, et al. (2007 Sep 5). Identification of a guanine nucleotide exchange factor for Arf3, the yeast orthologue of mammalian Arf6.

Smaczynska-de Rooij II, et al. (2008 Apr). Yeast Arf3p modulates plasma membrane PtdIns(4,5)P2 levels to facilitate endocytosis.

Tsai PC, et al. (2008 Jun 13). Afi1p functions as an Arf3p polarization-specific docking factor for development of polarity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03243
EOG89W0W6

sce:SYT1

Genes: 5

SGD Description
Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain


References

Jones S, et al. (1999 Aug). Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers.

Yu JW, et al. (2004 Mar 12). Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03244
EOG89W0W6

sce:absent

Genes: 2

PomBase Description
guanyl-nucleotide exchange factor Syt22


References

Fujita A, et al. (2009 May). Fission yeast syt22 protein, a putative Arf guanine nucleotide exchange factor, is necessary for new end take off.

Fujita A, et al. (2011 Aug). Fission yeast ucp3 gene encodes a putative Arf6 GTPase-activating protein.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%