FOG03211
EOG8NP5N2

sce:ERC1

Genes: 32

SGD Description
Member of the multi-drug and toxin extrusion (MATE) family; the MATE family is part of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine


AspGD Description
Ortholog(s) have role in S-adenosylmethionine biosynthetic process and fungal-type vacuole membrane localization


References

Shiomi N, et al. (1990 May). Production of S-adenosyl-L-methionine by Saccharomyces cerevisiae cells carrying a gene for ethionine resistance.

Shiomi N, et al. (1995 Jan). Improvement of S-adenosylmethionine production by integration of the ethionine-resistance gene into chromosomes of the yeast Saccharomyces cerevisiae.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%

FOG03212
EOG89P8FF
EOG8NP5N2

sce:TDP1

Genes: 26

SGD Description
Tyrosyl-DNA phosphodiesterase I; hydrolyzes 3' and 5'-phosphotyrosyl bonds; involved in the repair of DNA lesions created by topoisomerase I and topoisomerase II; mutations in human homolog result in the neurodegenerative disease SCANI


PomBase Description
tyrosyl-DNA phosphodiesterase Tdp1


AspGD Description
Ortholog(s) have nucleus localization


References

Pouliot JJ, et al. (1999 Oct 15). Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes.

Teixeira MT, et al. (2002 Aug 23). Genome-wide nuclear morphology screen identifies novel genes involved in nuclear architecture and gene-silencing in Saccharomyces cerevisiae.

Nitiss KC, et al. (2006 Jun 13). Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.

He X, et al. (2007 Sep 28). Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03213
EOG8NP5N2

sce:absent

Genes: 25

PomBase Description
MatE family transmembrane transporter (predicted)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 25 genes with posterior transmembrane prediction > 50%

FOG03214
EOG8NP5N2

sce:absent

Genes: 23

PomBase Description
MatE family transmembrane transporter (predicted)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 23 genes with posterior transmembrane prediction > 50%

FOG03215
EOG8NP5N2

sce:absent

Genes: 23

SGD Description
Putative protein of unknown function; member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 23 genes with posterior transmembrane prediction > 50%

FOG03216
EOG8NP5N2

sce:absent

Genes: 7

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG03217
EOG8NP5N2

sce:absent

Genes: 5

PomBase Description
MatE family transmembrane transporter (predicted)


AspGD Description
Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%