FOG02985
EOG8PRR7P

sce:KTR1

Genes: 40

SGD Description
Alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family; relocalizes from vacuole to cytoplasm upon DNA replication stress


PomBase Description
alpha-1,2-mannosyltransferase Omh1


AspGD Description
Alpha-1,2-mannosyltransferase


References

Hill K, et al. (1992 Feb). Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins.

Romero PA, et al. (1997 Jan 15). Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris.

Buurman ET, et al. (1998 Jun 23). Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans.

Munro CA, et al. (2005 Jan 14). Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 12 genes with posterior transmembrane prediction > 50%

FOG02986
EOG8PRR7P

sce:KTR4

Genes: 38

SGD Description
Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain


AspGD Description
Ortholog(s) have mannosylphosphate transferase activity, mannosyltransferase activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%

FOG02987
EOG8PRR7P

sce:KTR5;KTR7

Genes: 31

SGD Description
Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR5 has a paralog, KTR7, that arose from the whole genome duplication|Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR7 has a paralog, KTR5, that arose from the whole genome duplication


PomBase Description
alpha-1,2-mannosyltransferase Omh4 (predicted)|alpha-1,2-mannosyltransferase Omh5 (predicted)


AspGD Description
Ortholog(s) have cytosol, nucleus localization


References

Lussier M, et al. (1997 Mar 15). Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism.

Ikeda Y, et al. (2009 Feb). Identification and characterization of a gene required for alpha1,2-mannose extension in the O-linked glycan synthesis pathway in Schizosaccharomyces pombe.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 17 genes with posterior transmembrane prediction > 50%

FOG02988
EOG8PRR7P

sce:KTR2;YUR1

Genes: 29

SGD Description
Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR2 has a paralog, YUR1, that arose from the whole genome duplication|Mannosyltransferase involved in protein N-glycosylation; member of the KTR1 family; located in the Golgi apparatus; YUR1 has a paralog, KTR2, that arose from the whole genome duplication


PomBase Description
alpha-1,2-mannosyltransferase Omh3 (predicted)


References

Foreman PK, et al. (1991 May 25). The Saccharomyces cerevisiae RPB4 gene is tightly linked to the TIF2 gene.

Lussier M, et al. (1993 Oct). KTR2: a new member of the KRE2 mannosyltransferase gene family.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%

FOG02989
EOG8PRR7P

sce:KRE2

Genes: 25

SGD Description
Alpha1,2-mannosyltransferase of the Golgi; involved in protein mannosylation; KRE2 has a paralog, KTR6, that arose from the whole genome duplication


References

Hill K, et al. (1992 Feb). Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins.

Häusler A, et al. (1992 Feb). Glycosylation in Saccharomyces cerevisiae: cloning and characterization of an alpha-1,2-mannosyltransferase structural gene.

Kölling R, et al. (1994 Sep). Nucleotide sequence of the SAC2 gene of Saccharomyces cerevisiae.

Munro CA, et al. (2005 Jan 14). Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 8 genes with posterior transmembrane prediction > 50%

FOG02990
EOG8PRR7P

sce:absent

Genes: 18

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG02991
EOG8PRR7P

sce:KTR3

Genes: 7

SGD Description
Putative alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; relocalizes from nucleus to vacuole upon DNA replication stress


References

Inadome H, et al. (2005 Sep). Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG02992
EOG8PRR7P

sce:absent

Genes: 7

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02993
EOG8PRR7P

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02994
EOG8PRR7P

sce:absent

Genes: 3

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02995
EOG8PRR7P

sce:absent

Genes: 4

PomBase Description
alpha-1,2-mannosyltransferase Omh2 (predicted)


References

Ikeda Y, et al. (2009 Feb). Identification and characterization of a gene required for alpha1,2-mannose extension in the O-linked glycan synthesis pathway in Schizosaccharomyces pombe.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%