FOG02822
EOG87SQW3

sce:DNM1

Genes: 33

SGD Description
Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance


PomBase Description
mitochondrial dynamin family GTPase Dnm1


AspGD Description
Ortholog(s) have GTPase activity, protein homodimerization activity


References

Gammie AE, et al. (1995 Aug). DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast.

Bleazard W, et al. (1999 Sep). The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.

Tieu Q, et al. (2000 Oct 16). Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division.

Fukushima NH, et al. (2001 Sep). The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission.

Cerveny KL, et al. (2003 Oct). The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria.

Koirala S, et al. (2013 Apr 9). Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02823
EOG87SQW3

sce:VPS1

Genes: 36

SGD Description
Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, endocytosis, late Golgi-retention of some proteins, regulation of peroxisome biogenesis


PomBase Description
dynamin family protein Vps1


AspGD Description
Protein with similarity to GTP-binding protein Vps1p of S. cerevisiae


References

Rothman JH, et al. (1990 Jun 15). A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting.

Yeh E, et al. (1991 Feb 21). A dynamin-like protein encoded by the yeast sporulation gene SPO15.

Wilsbach K, et al. (1993 Aug). Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae.

Tarutani Y, et al. (2001 May 2). Cloning and characterization of Aspergillus nidulans vpsA gene which is involved in vacuolar biogenesis.

Jourdain I, et al. (2008 Mar). Dynamin-dependent biogenesis, cell cycle regulation and mitochondrial association of peroxisomes in fission yeast.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Jourdain I, et al. (2009 Aug). The dynamin related protein Dnm1 fragments mitochondria in a microtubule-dependent manner during the fission yeast cell cycle.

Röthlisberger S, et al. (2009 Dec). The dynamin-related protein Vps1 regulates vacuole fission, fusion and tubulation in the fission yeast, Schizosaccharomyces pombe.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Sirotkin V, et al. (2010 Aug 15). Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast.

Mikawa T, et al. (2010 Mar). Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Fang Y, et al. (2012 Apr). A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Encinar del Dedo J, et al. (2014 Oct). Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Park DS, et al. (2015 Feb). Negative regulation of the vacuole-mediated resistance to K(+) stress by a novel C2H2 zinc finger transcription factor encoded by aslA in Aspergillus nidulans.

Palmer SE, et al. (2015 Mar 30). A dynamin-actin interaction is required for vesicle scission during endocytosis in yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%