FOG02741
EOG8G79DQ
EOG8SN03R

sce:FLC1;FLC3

Genes: 28

SGD Description
Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC1 has a paralog, FLC3, that arose from the whole genome duplication|Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER; FLC3 has a paralog, FLC1, that arose from the whole genome duplication


References

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Protchenko O, et al. (2006 Jul 28). A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
28 genes with posterior transmembrane prediction > 50%


FOG02742
EOG8G79DQ

sce:FLC2;

Genes: 36

SGD Description
Putative calcium channel involved in calcium release under hypotonic stress; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC2 has a paralog, YOR365C, that arose from the whole genome duplication|Putative protein of unknown function; not an essential protein; YOR365C has a paralog, FLC2, that arose from the whole genome duplication


PomBase Description
TRP-like ion channel Pkd2


AspGD Description
Ortholog of Aspergillus tubingensis : Asptu1_0039844, Aspergillus brasiliensis : Aspbr1_0118922, Aspergillus kawachii : Aspka1_0173805 and Aspergillus acidus : Aspfo1_0039768|Ortholog(s) have FAD transmembrane transporter activity, calcium channel activity


References

Kratzer S, et al. (1995 Aug 8). Carbon source-dependent regulation of the acetyl-coenzyme A synthetase-encoding gene ACS1 from Saccharomyces cerevisiae.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Protchenko O, et al. (2006 Jul 28). A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
36 genes with posterior transmembrane prediction > 50%


FOG02743
EOG8SN03R

sce:absent

Genes: 15
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
15 genes with posterior transmembrane prediction > 50%


FOG02744
EOG8SN03R

sce:absent

Genes: 9

PomBase Description
TRP-like ion channel (predicted)


AspGD Description
Ortholog(s) have extracellular region localization


References

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Ma Y, et al. (2011). Transient receptor potential (TRP) and Cch1-Yam8 channels play key roles in the regulation of cytoplasmic Ca2+ in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Jaiseng W, et al. (2012). Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast.

Zhou X, et al. (2013). A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
9 genes with posterior transmembrane prediction > 50%


FOG02745
EOG8G79DQ

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%


FOG02746
EOG8SN03R

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%