FOG02739
EOG8Z6148

sce:PXA2

Genes: 30

SGD Description
Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa1p


AspGD Description
Ortholog(s) have ATPase activity, coupled to transmembrane movement of substances activity, role in fatty acid transmembrane transport and integral component of peroxisomal membrane localization


References

Hettema EH, et al. (1996 Aug 1). The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

Shani N, et al. (1996 Oct 15). A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

Galagan JE, et al. (2005 Dec 22). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.

Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%

FOG02740
EOG8Z6148

sce:PXA1

Genes: 30

SGD Description
Subunit of a heterodimeric peroxisomal ABC transport complex; required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; complex also includes Pxa2p


AspGD Description
Ortholog(s) have ATPase activity, coupled to transmembrane movement of substances activity, role in fatty acid transport and integral component of peroxisomal membrane, peroxisomal importomer complex localization


References

Shani N, et al. (1995 Jun 20). PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.

Hettema EH, et al. (1996 Aug 1). The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

Swartzman EE, et al. (1996 Feb). The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae.

Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%