FOG02706
EOG88W9JS

sce:ORT1

Genes: 35

SGD Description
Ornithine transporter of the mitochondrial inner membrane; exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome


AspGD Description
Ortholog(s) have L-ornithine transmembrane transporter activity, role in arginine biosynthetic process, mitochondrial ornithine transport and mitochondrial envelope localization


References

Crabeel M, et al. (1996 Oct 4). The ARG11 gene of Saccharomyces cerevisiae encodes a mitochondrial integral membrane protein required for arginine biosynthesis.

Palmieri L, et al. (1997 Jun 30). Identification of the yeast ARG-11 gene as a mitochondrial ornithine carrier involved in arginine biosynthesis.

Sun J, et al. (1998 Mar). Sequencing of a gene encoding a member of the mitochondrial carrier family of transport proteins from Aspergillus nidulans.

Oberegger H, et al. (2001 Sep). SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans.

Haas H, et al. (2003 Sep). Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%