FOG02421
EOG8PVMDS
EOG8VT4C9
sce:absent
Genes: 138
EOG8PVMDS
EOG8VT4C9
sce:absent
Genes: 138
Protein description
abc transporter
PomBase Description
ABC transmembrane transporter Ybt1|glutathione S-conjugate-exporting ATPase Abc4
AspGD Description
Ortholog(s) have glutathione S-conjugate-transporting ATPase activity and role in cellular response to cadmium ion, glutathione transmembrane import into vacuole, secondary metabolite biosynthetic process|Ortholog(s) have role in secondary metabolite biosynthetic process|Ortholog(s) have role in secondary metabolite biosynthetic process|Has domain(s) with predicted ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, nucleoside-triphosphatase activity, nucleotide binding activity and role in transmembrane transport
References
Theiss S, et al. (2002 Feb). Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.
Gaur M, et al. (2005). Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans.
Iwaki T, et al. (2006 Aug). A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant.
Liu NN, et al. (2010 Aug). A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.
Mendoza-Cózatl DG, et al. (2010 Dec 24). Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
Akiyama K, et al. (2011 Jan). Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe.
Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.
Wang L, et al. (2012). Proteomic analysis of Rta2p-dependent raft-association of detergent-resistant membranes in Candida albicans.
Kawashima SA, et al. (2012 Jul 27). Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.
Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
138 genes with posterior transmembrane prediction > 50% |
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FOG02422
EOG8VT4C9
sce:YOR1
Genes: 1
EOG8VT4C9
sce:YOR1
Genes: 1
SGD Description
Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR)
References
Katzmann DJ, et al. (1995 Dec). Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae.
Hikkel I, et al. (2003 Mar 28). A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.
Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG02423
EOG8PVMDS
EOG8VT4C9
sce:YCF1
Genes: 37
EOG8PVMDS
EOG8VT4C9
sce:YCF1
Genes: 37
SGD Description
Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR
PomBase Description
ABC transmembrane transporter Abc3, unknown specificity|glutathione S-conjugate-exporting ATPase Abc2
AspGD Description
ABC metal ion transporter
References
Szczypka MS, et al. (1994 Sep 9). A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.
Li ZS, et al. (1996 Mar 15). The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump.
Petrovic S, et al. (2000 Apr). The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae.
Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
37 genes with posterior transmembrane prediction > 50% |
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FOG02424
EOG8VT4C9
sce:BPT1
Genes: 1
EOG8VT4C9
sce:BPT1
Genes: 1
SGD Description
ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p
References
Boy-Marcotte E, et al. (1989 Apr 15). The C-terminal part of a gene partially homologous to CDC 25 gene suppresses the cdc25-5 mutation in Saccharomyces cerevisiae.
Petrovic S, et al. (2000 Apr). The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae.
Klein M, et al. (2002 Jun 5). The ATP-binding cassette (ABC) transporter Bpt1p mediates vacuolar sequestration of glutathione conjugates in yeast.
Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG02425
sce:absent
Genes: 0
sce:absent
Genes: 0
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG02426
EOG8PVMDS
sce:YBT1
Genes: 1
EOG8PVMDS
sce:YBT1
Genes: 1
SGD Description
Transporter of the ATP-binding cassette (ABC) family; involved in bile acid transport; negative regulator of vacuole fusion; regulates release of lumenal Ca2+ stores; similar to mammalian bile transporters; YBT1 has a paralog, VMR1, that arose from the whole genome duplication
References
Cusick ME, et al. (1994 Mar 11). RNP1, a new ribonucleoprotein gene of the yeast Saccharomyces cerevisiae.
Ortiz DF, et al. (1997 Jun 13). A yeast ATP-binding cassette-type protein mediating ATP-dependent bile acid transport.
Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Gulshan K, et al. (2011 Sep). Vacuolar import of phosphatidylcholine requires the ATP-binding cassette transporter Ybt1.
Sasser TL, et al. (2012 Dec 15). The yeast vacuolar ABC transporter Ybt1p regulates membrane fusion through Ca2+ transport modulation.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG02427
EOG8VT4C9
sce:absent
Genes: 2
EOG8VT4C9
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG02428
EOG8PVMDS
sce:NFT1;VMR1;
Genes: 45
EOG8PVMDS
sce:NFT1;VMR1;
Genes: 45
SGD Description
Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein|Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication|Putative transporter of the MRP subfamily; contains a stop codon in S288C; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein
AspGD Description
Putative bile acid ABC transporter; induced by exposure to DTT|Has domain(s) with predicted ATP binding, ATPase activity, coupled to transmembrane movement of substances activity, role in transmembrane transport and integral component of membrane localization
References
Decottignies A, et al. (1997 Feb). Complete inventory of the yeast ABC proteins.
Rutherford JC, et al. (2003 Jul 25). Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements.
van Bakel H, et al. (2005 Aug 11). Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism.
Lahue E, et al. (2005 May). The Saccharomyces cerevisiae Sub2 protein suppresses heterochromatic silencing at telomeres and subtelomeric genes.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
44 genes with posterior transmembrane prediction > 50% |
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FOG02429
EOG8PVMDS
sce:absent
Genes: 4
EOG8PVMDS
sce:absent
Genes: 4
AspGD Description
Has domain(s) with predicted ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, nucleoside-triphosphatase activity, nucleotide binding activity and role in transmembrane transport
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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