FOG02308
EOG8DR7TX

sce:MES1

Genes: 34

SGD Description
Methionyl-tRNA synthetase; forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs


PomBase Description
cytoplasmic methionine-tRNA ligase Mrs1 (predicted)


AspGD Description
Ortholog(s) have cytosol localization


References

Walter P, et al. (1983 May). Primary structure of the Saccharomyces cerevisiae gene for methionyl-tRNA synthetase.

Gibson BW, et al. (1984 Apr). Strategy for the mass spectrometric verification and correction of the primary structures of proteins deduced from their DNA sequences.

Fasiolo F, et al. (1985 Dec 15). Cytoplasmic methionyl-tRNA synthetase from Bakers' yeast. A monomer with a post-translationally modified N terminus.

Chatton B, et al. (1987 Nov 5). Cloning and characterization of the yeast methionyl-tRNA synthetase mutation mes1.

Despons L, et al. (1991 Sep 9). Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase.

Simos G, et al. (1996 Oct 1). The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl- and glutamyl-tRNA synthetases.

Simos G, et al. (1998 Jan). A conserved domain within Arc1p delivers tRNA to aminoacyl-tRNA synthetases.

Galani K, et al. (2001 Dec 3). The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p.

Deinert K, et al. (2001 Feb 23). Arc1p organizes the yeast aminoacyl-tRNA synthetase complex and stabilizes its interaction with the cognate tRNAs.

Simader H, et al. (2006). Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%