FOG02300
EOG8P5HRW

sce:FRS2

Genes: 35

SGD Description
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar


PomBase Description
cytoplasmic phenylalanine-tRNA ligase alpha subunit Frs2 (predicted)


AspGD Description
Has domain(s) with predicted ATP binding, aminoacyl-tRNA ligase activity, tRNA binding activity, role in tRNA aminoacylation and cytoplasm localization


References

Sanni A, et al. (1988 Oct 25). Structure and expression of the genes encoding the alpha and beta subunits of yeast phenylalanyl-tRNA synthetase.

Fasiolo F, et al. (1989 Jan 2). Identification of the major tRNA(Phe) binding domain in the tetrameric structure of cytoplasmic phenylalanyl-tRNA synthetase from baker's yeast.

Singh NK, et al. (1996). Fast dissociation of phe-tRNA synthetase from Aspergillus nidulans immobilized on sepharose-6B column by NaCl.

Garrels JI, et al. (1997 Aug). Proteome studies of Saccharomyces cerevisiae: identification and characterization of abundant proteins.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30<sup>Fft3</sup> induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%