FOG02090
EOG8RFJ9N

sce:CDS1

Genes: 34

SGD Description
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids


PomBase Description
phosphatidate cytidylyltransferase (predicted)


AspGD Description
Protein similar to phosphatidate cytidylyltransferase


References

Kelley MJ, et al. (1987 Oct 25). Purification and characterization of CDP-diacylglycerol synthase from Saccharomyces cerevisiae.

Kinney AJ, et al. (1990 Jul). Enzymes of phosphoinositide synthesis in secretory vesicles destined for the plasma membrane in Saccharomyces cerevisiae.

Gaynor PM, et al. (1992 Sep). Regulation of CDP-diacylglycerol synthesis and utilization by inositol and choline in Schizosaccharomyces pombe.

Shen H, et al. (1996 Jan 12). The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth.

Shen H, et al. (1996 Nov 15). Reduction of CDP-diacylglycerol synthase activity results in the excretion of inositol by Saccharomyces cerevisiae.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Tamura Y, et al. (2013 May 7). Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%