FOG02078
EOG8MGQQC

sce:ATG15

Genes: 34

SGD Description
Lipase required for intravacuolar lysis of autophagic and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway


PomBase Description
autophagy associated lipase Atg15


AspGD Description
Vacuolar lipase; predicted role in autophagy


References

Teter SA, et al. (2001 Jan 19). Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase.

Hutchins MU, et al. (2001 Jun 8). Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae.

Epple UD, et al. (2001 Oct). Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole.

Epple UD, et al. (2003 Mar 7). Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function?

Tang F, et al. (2008 Oct). A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery.

Mukaiyama H, et al. (2009 Dec). Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation.

Suzuki SW, et al. (2011 Feb 25). Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction.

Arlt H, et al. (2011 Nov). An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking.

Lu KY, et al. (2012 Nov). Profiling lipid-protein interactions using nonquenched fluorescent liposomal nanovesicles and proteome microarrays.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 19 genes with posterior transmembrane prediction > 50%